SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000012048 BRCA1 ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.988493 View
ENSG00000096717 SIRT1 ENSG00000154310 TNIK H. sapiens SDL Slorth 0.984939 View
ENSG00000080824 HSP90AA1 ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.983861 View
ENSG00000096717 SIRT1 ENSG00000143556 S100A7 H. sapiens SDL Slorth 0.983759 View
ENSG00000096717 SIRT1 ENSG00000160007 ARHGAP35 H. sapiens SDL Slorth 0.9828 View
ENSG00000096717 SIRT1 ENSG00000184675 AMER1 H. sapiens SDL Slorth 0.981878 View
ENSG00000096717 SIRT1 ENSG00000175093 SPSB4 H. sapiens SDL Slorth 0.981429 View
ENSG00000005339 CREBBP ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.981065 View
ENSG00000096717 SIRT1 ENSG00000102225 CDK16 H. sapiens SDL Slorth 0.981037 View
ENSG00000096717 SIRT1 ENSG00000185386 MAPK11 H. sapiens SDL Slorth 0.98087 View
ENSG00000096717 SIRT1 ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.980389 View
ENSG00000096717 SIRT1 ENSG00000156299 TIAM1 H. sapiens SDL Slorth 0.980334 View
ENSG00000096717 SIRT1 ENSG00000188130 MAPK12 H. sapiens SDL Slorth 0.980197 View
ENSG00000096717 SIRT1 ENSG00000180008 SOCS4 H. sapiens SDL Slorth 0.980005 View
ENSG00000096717 SIRT1 ENSG00000100505 TRIM9 H. sapiens SDL Slorth 0.979684 View
ENSG00000096717 SIRT1 ENSG00000114423 CBLB H. sapiens SSL Slorth 0.979456 View
ENSG00000096717 SIRT1 ENSG00000100297 MCM5 H. sapiens SSL Slorth 0.979048 View
ENSG00000096717 SIRT1 ENSG00000151422 FER H. sapiens SDL Slorth 0.978941 View
ENSG00000096717 SIRT1 ENSG00000168148 HIST3H3 H. sapiens SSL Slorth 0.978779 View
ENSG00000096717 SIRT1 ENSG00000170345 FOS H. sapiens SSL Slorth 0.978625 View
ENSG00000096717 SIRT1 ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.978383 View
ENSG00000096717 SIRT1 ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.978236 View
ENSG00000096717 SIRT1 ENSG00000130939 UBE4B H. sapiens SSL Slorth 0.978102 View
ENSG00000096717 SIRT1 ENSG00000136450 SRSF1 H. sapiens SSL Slorth 0.978047 View
ENSG00000096717 SIRT1 ENSG00000157106 SMG1 H. sapiens SSL Slorth 0.977679 View
ENSG00000096717 SIRT1 ENSG00000109320 NFKB1 H. sapiens SSL Slorth 0.977668 View
ENSG00000096717 SIRT1 ENSG00000196628 TCF4 H. sapiens SSL Slorth 0.977662 View
ENSG00000096717 SIRT1 ENSG00000163932 PRKCD H. sapiens SSL Slorth 0.977616 View
ENSG00000096717 SIRT1 ENSG00000198517 MAFK H. sapiens SDL Slorth 0.977485 View
ENSG00000096717 SIRT1 ENSG00000244405 ETV5 H. sapiens SDL Slorth 0.977485 View
ENSG00000096717 SIRT1 ENSG00000132170 PPARG H. sapiens SSL Slorth 0.977285 View
ENSG00000096717 SIRT1 ENSG00000108094 CUL2 H. sapiens SSL Slorth 0.977282 View
ENSG00000096717 SIRT1 ENSG00000123405 NFE2 H. sapiens SDL Slorth 0.977232 View
ENSG00000096717 SIRT1 ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.977099 View
ENSG00000096717 SIRT1 ENSG00000131196 NFATC1 H. sapiens SDL Slorth 0.97697 View
ENSG00000096717 SIRT1 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.976902 View
ENSG00000096717 SIRT1 ENSG00000111276 CDKN1B H. sapiens SSL Slorth 0.976843 View
ENSG00000096717 SIRT1 ENSG00000169714 CNBP H. sapiens SDL Slorth 0.976788 View
ENSG00000096717 SIRT1 ENSG00000128607 KLHDC10 H. sapiens SDL Slorth 0.97674 View
ENSG00000096717 SIRT1 ENSG00000110330 BIRC2 H. sapiens SSL Slorth 0.976737 View