SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000115221 ITGB6 H. sapiens SDL Slorth 0.967415 View
ENSG00000070010 UFD1L ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.967367 View
ENSG00000096717 SIRT1 ENSG00000188612 SUMO2 H. sapiens SSL Slorth 0.967305 View
ENSG00000080815 PSEN1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.967271 View
ENSG00000096717 SIRT1 ENSG00000165671 NSD1 H. sapiens SDL Slorth 0.967215 View
ENSG00000096717 SIRT1 ENSG00000144668 ITGA9 H. sapiens SDL Slorth 0.967157 View
ENSG00000096717 SIRT1 ENSG00000204389 HSPA1A H. sapiens SDL Slorth 0.967149 View
ENSG00000096717 SIRT1 ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.967137 View
ENSG00000096717 SIRT1 ENSG00000141027 NCOR1 H. sapiens SSL Slorth 0.967134 View
ENSG00000096717 SIRT1 ENSG00000166197 NOLC1 H. sapiens SSL Slorth 0.967124 View
ENSG00000087510 TFAP2C ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.967107 View
ENSG00000096717 SIRT1 ENSG00000119866 BCL11A H. sapiens SDL Slorth 0.967086 View
ENSG00000096717 SIRT1 ENSG00000105229 PIAS4 H. sapiens SSL Slorth 0.96707 View
ENSG00000096717 SIRT1 ENSG00000118689 FOXO3 H. sapiens SSL Slorth 0.967033 View
ENSG00000096717 SIRT1 ENSG00000184634 MED12 H. sapiens SSL Slorth 0.967018 View
ENSG00000096717 SIRT1 ENSG00000198625 MDM4 H. sapiens SSL Slorth 0.967004 View
ENSG00000096717 SIRT1 ENSG00000138756 BMP2K H. sapiens SDL Slorth 0.966963 View
ENSG00000096717 SIRT1 ENSG00000157933 SKI H. sapiens SSL Slorth 0.966905 View
ENSG00000096717 SIRT1 ENSG00000100092 SH3BP1 H. sapiens SDL Slorth 0.9669 View
ENSG00000096717 SIRT1 ENSG00000134954 ETS1 H. sapiens SSL Slorth 0.966851 View
ENSG00000096717 SIRT1 ENSG00000106546 AHR H. sapiens SSL Slorth 0.966846 View
ENSG00000096717 SIRT1 ENSG00000136807 CDK9 H. sapiens SSL Slorth 0.966723 View
ENSG00000096717 SIRT1 ENSG00000163938 GNL3 H. sapiens SSL Slorth 0.966622 View
ENSG00000096717 SIRT1 ENSG00000198561 CTNND1 H. sapiens SSL Slorth 0.966616 View
ENSG00000096717 SIRT1 ENSG00000100650 SRSF5 H. sapiens SSL Slorth 0.966547 View
ENSG00000096717 SIRT1 ENSG00000165506 DNAAF2 H. sapiens SDL Slorth 0.966495 View
ENSG00000096717 SIRT1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.966468 View
ENSG00000096717 SIRT1 ENSG00000101161 PRPF6 H. sapiens SSL Slorth 0.966415 View
ENSG00000096717 SIRT1 ENSG00000173801 JUP H. sapiens SDL Slorth 0.966412 View
ENSG00000004700 RECQL ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.966383 View
ENSG00000078747 ITCH ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.966372 View
ENSG00000096717 SIRT1 ENSG00000100968 NFATC4 H. sapiens SDL Slorth 0.966359 View
ENSG00000096717 SIRT1 ENSG00000097046 CDC7 H. sapiens SSL Slorth 0.966326 View
ENSG00000096717 SIRT1 ENSG00000196235 SUPT5H H. sapiens SSL Slorth 0.96631 View
ENSG00000096717 SIRT1 ENSG00000185513 L3MBTL1 H. sapiens SDL Slorth 0.966289 View
ENSG00000078140 UBE2K ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.966287 View
ENSG00000073111 MCM2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.966245 View
ENSG00000096717 SIRT1 ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.966183 View
ENSG00000096717 SIRT1 ENSG00000159216 RUNX1 H. sapiens SDL Slorth 0.966173 View
ENSG00000096717 SIRT1 ENSG00000161547 SRSF2 H. sapiens SSL Slorth 0.96604 View