SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000021574 SPAST ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.969097 View
ENSG00000096717 SIRT1 ENSG00000171791 BCL2 H. sapiens SSL Slorth 0.969046 View
ENSG00000078403 MLLT10 ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.968902 View
ENSG00000096717 SIRT1 ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.968854 View
ENSG00000096717 SIRT1 ENSG00000103479 RBL2 H. sapiens SSL Slorth 0.968811 View
ENSG00000096717 SIRT1 ENSG00000129911 KLF16 H. sapiens SDL Slorth 0.968796 View
ENSG00000077279 DCX ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.968668 View
ENSG00000096717 SIRT1 ENSG00000117748 RPA2 H. sapiens SSL Slorth 0.968656 View
ENSG00000096717 SIRT1 ENSG00000108924 HLF H. sapiens SDL Slorth 0.968651 View
ENSG00000096717 SIRT1 ENSG00000109062 SLC9A3R1 H. sapiens SSL Slorth 0.968648 View
ENSG00000096717 SIRT1 ENSG00000167085 PHB H. sapiens SSL Slorth 0.968641 View
ENSG00000004897 CDC27 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.968627 View
ENSG00000096717 SIRT1 ENSG00000104365 IKBKB H. sapiens SSL Slorth 0.96849 View
ENSG00000096717 SIRT1 ENSG00000164032 H2AFZ H. sapiens SDL Slorth 0.968481 View
ENSG00000096717 SIRT1 ENSG00000136997 MYC H. sapiens SSL Slorth 0.968466 View
ENSG00000096717 SIRT1 ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.968451 View
ENSG00000096717 SIRT1 ENSG00000096968 JAK2 H. sapiens SSL Slorth 0.968435 View
ENSG00000096717 SIRT1 ENSG00000168610 STAT3 H. sapiens SSL Slorth 0.968351 View
ENSG00000096717 SIRT1 ENSG00000124813 RUNX2 H. sapiens SSL Slorth 0.968313 View
ENSG00000096717 SIRT1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968199 View
ENSG00000096717 SIRT1 ENSG00000162775 RBM15 H. sapiens SDL Slorth 0.96807 View
ENSG00000072736 NFATC3 ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.967932 View
ENSG00000096717 SIRT1 ENSG00000176720 BOK H. sapiens SDL Slorth 0.967913 View
ENSG00000096717 SIRT1 ENSG00000107929 LARP4B H. sapiens SDL Slorth 0.967888 View
ENSG00000096717 SIRT1 ENSG00000112144 ICK H. sapiens SDL Slorth 0.967839 View
ENSG00000096717 SIRT1 ENSG00000140464 PML H. sapiens SSL Slorth 0.967788 View
ENSG00000096717 SIRT1 ENSG00000100138 SNU13 H. sapiens SSL Slorth 0.967726 View
ENSG00000096717 SIRT1 ENSG00000155846 PPARGC1B H. sapiens SDL Slorth 0.967717 View
ENSG00000096717 SIRT1 ENSG00000100503 NIN H. sapiens SDL Slorth 0.967716 View
ENSG00000079335 CDC14A ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.967704 View
ENSG00000096717 SIRT1 ENSG00000100401 RANGAP1 H. sapiens SSL Slorth 0.967703 View
ENSG00000096717 SIRT1 ENSG00000148516 ZEB1 H. sapiens SDL Slorth 0.967684 View
ENSG00000096717 SIRT1 ENSG00000169372 CRADD H. sapiens SDL Slorth 0.967668 View
ENSG00000096717 SIRT1 ENSG00000123124 WWP1 H. sapiens SSL Slorth 0.96764 View
ENSG00000096717 SIRT1 ENSG00000108055 SMC3 H. sapiens SDL Slorth 0.96759 View
ENSG00000096717 SIRT1 ENSG00000108984 MAP2K6 H. sapiens SDL Slorth 0.967572 View
ENSG00000096717 SIRT1 ENSG00000134371 CDC73 H. sapiens SDL Slorth 0.967531 View
ENSG00000096717 SIRT1 ENSG00000119041 GTF3C3 H. sapiens SDL Slorth 0.967523 View
ENSG00000096717 SIRT1 ENSG00000101213 PTK6 H. sapiens SDL Slorth 0.967448 View
ENSG00000096717 SIRT1 ENSG00000100359 SGSM3 H. sapiens SDL Slorth 0.967442 View