SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000165409 TSHR H. sapiens SDL Slorth 0.964369 View
ENSG00000096717 SIRT1 ENSG00000163947 ARHGEF3 H. sapiens SDL Slorth 0.964366 View
ENSG00000096717 SIRT1 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.96433 View
ENSG00000096717 SIRT1 ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.96433 View
ENSG00000077935 SMC1B ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.964329 View
ENSG00000096717 SIRT1 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.964309 View
ENSG00000096717 SIRT1 ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.964304 View
ENSG00000096717 SIRT1 ENSG00000153147 SMARCA5 H. sapiens SSL Slorth 0.964281 View
ENSG00000096717 SIRT1 ENSG00000108984 MAP2K6 H. sapiens SSL Slorth 0.964224 View
ENSG00000096717 SIRT1 ENSG00000145741 BTF3 H. sapiens SSL Slorth 0.964191 View
ENSG00000096717 SIRT1 ENSG00000162909 CAPN2 H. sapiens SSL Slorth 0.964191 View
ENSG00000096717 SIRT1 ENSG00000170142 UBE2E1 H. sapiens SSL Slorth 0.964177 View
ENSG00000096717 SIRT1 ENSG00000188021 UBQLN2 H. sapiens SSL Slorth 0.964138 View
ENSG00000096717 SIRT1 ENSG00000175197 DDIT3 H. sapiens SSL Slorth 0.964126 View
ENSG00000096717 SIRT1 ENSG00000147162 OGT H. sapiens SSL Slorth 0.96405 View
ENSG00000096717 SIRT1 ENSG00000120837 NFYB H. sapiens SDL Slorth 0.964002 View
ENSG00000096717 SIRT1 ENSG00000128245 YWHAH H. sapiens SSL Slorth 0.963994 View
ENSG00000096717 SIRT1 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.963992 View
ENSG00000096717 SIRT1 ENSG00000162231 NXF1 H. sapiens SSL Slorth 0.963973 View
ENSG00000096717 SIRT1 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.963967 View
ENSG00000096717 SIRT1 ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.963901 View
ENSG00000096717 SIRT1 ENSG00000135723 FHOD1 H. sapiens SDL Slorth 0.963876 View
ENSG00000096717 SIRT1 ENSG00000100722 ZC3H14 H. sapiens SSL Slorth 0.96385 View
ENSG00000096717 SIRT1 ENSG00000163098 BIRC8 H. sapiens SDL Slorth 0.96382 View
ENSG00000096717 SIRT1 ENSG00000169800 RBMY1F H. sapiens SDL Slorth 0.963817 View
ENSG00000096717 SIRT1 ENSG00000113141 IK H. sapiens SSL Slorth 0.963778 View
ENSG00000096717 SIRT1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.963777 View
ENSG00000096717 SIRT1 ENSG00000135090 TAOK3 H. sapiens SDL Slorth 0.963721 View
ENSG00000096717 SIRT1 ENSG00000169139 UBE2V2 H. sapiens SDL Slorth 0.963712 View
ENSG00000096717 SIRT1 ENSG00000196218 RYR1 H. sapiens SDL Slorth 0.963688 View
ENSG00000096717 SIRT1 ENSG00000114030 KPNA1 H. sapiens SSL Slorth 0.963683 View
ENSG00000096717 SIRT1 ENSG00000172059 KLF11 H. sapiens SDL Slorth 0.963633 View
ENSG00000096717 SIRT1 ENSG00000160224 AIRE H. sapiens SDL Slorth 0.963632 View
ENSG00000096717 SIRT1 ENSG00000134982 APC H. sapiens SDL Slorth 0.963627 View
ENSG00000096717 SIRT1 ENSG00000157601 MX1 H. sapiens SDL Slorth 0.963578 View
ENSG00000096717 SIRT1 ENSG00000139842 CUL4A H. sapiens SSL Slorth 0.963578 View
ENSG00000096717 SIRT1 ENSG00000136810 TXN H. sapiens SSL Slorth 0.963447 View
ENSG00000096717 SIRT1 ENSG00000163743 RCHY1 H. sapiens SSL Slorth 0.963392 View
ENSG00000096717 SIRT1 ENSG00000108312 UBTF H. sapiens SSL Slorth 0.963271 View
ENSG00000096717 SIRT1 ENSG00000105254 TBCB H. sapiens SSL Slorth 0.963269 View