SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000120149 MSX2 H. sapiens SDL Slorth 0.970908 View
ENSG00000096717 SIRT1 ENSG00000122779 TRIM24 H. sapiens SSL Slorth 0.970871 View
ENSG00000096717 SIRT1 ENSG00000143190 POU2F1 H. sapiens SSL Slorth 0.97083 View
ENSG00000096717 SIRT1 ENSG00000147274 RBMX H. sapiens SSL Slorth 0.9708 View
ENSG00000096717 SIRT1 ENSG00000141380 SS18 H. sapiens SDL Slorth 0.970795 View
ENSG00000096717 SIRT1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.970733 View
ENSG00000096717 SIRT1 ENSG00000168283 BMI1 H. sapiens SSL Slorth 0.970731 View
ENSG00000096717 SIRT1 ENSG00000169891 REPS2 H. sapiens SDL Slorth 0.970657 View
ENSG00000096717 SIRT1 ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.970596 View
ENSG00000096717 SIRT1 ENSG00000168453 HR H. sapiens SDL Slorth 0.970594 View
ENSG00000096717 SIRT1 ENSG00000113575 PPP2CA H. sapiens SSL Slorth 0.970589 View
ENSG00000096717 SIRT1 ENSG00000175792 RUVBL1 H. sapiens SSL Slorth 0.970583 View
ENSG00000094804 CDC6 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.970583 View
ENSG00000096717 SIRT1 ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.970576 View
ENSG00000096717 SIRT1 ENSG00000197299 BLM H. sapiens SSL Slorth 0.970571 View
ENSG00000082146 STRADB ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.970522 View
ENSG00000096717 SIRT1 ENSG00000170734 POLH H. sapiens SSL Slorth 0.970483 View
ENSG00000096717 SIRT1 ENSG00000101966 XIAP H. sapiens SSL Slorth 0.970478 View
ENSG00000096717 SIRT1 ENSG00000127511 SIN3B H. sapiens SSL Slorth 0.970412 View
ENSG00000096717 SIRT1 ENSG00000140451 PIF1 H. sapiens SDL Slorth 0.970359 View
ENSG00000096717 SIRT1 ENSG00000150907 FOXO1 H. sapiens SSL Slorth 0.97031 View
ENSG00000096717 SIRT1 ENSG00000162367 TAL1 H. sapiens SSL Slorth 0.970305 View
ENSG00000096717 SIRT1 ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.97028 View
ENSG00000096717 SIRT1 ENSG00000159692 CTBP1 H. sapiens SSL Slorth 0.970212 View
ENSG00000096717 SIRT1 ENSG00000119403 PHF19 H. sapiens SDL Slorth 0.969992 View
ENSG00000096717 SIRT1 ENSG00000117399 CDC20 H. sapiens SSL Slorth 0.969927 View
ENSG00000096717 SIRT1 ENSG00000132341 RAN H. sapiens SSL Slorth 0.96989 View
ENSG00000085511 MAP3K4 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.969739 View
ENSG00000096717 SIRT1 ENSG00000121022 COPS5 H. sapiens SSL Slorth 0.969732 View
ENSG00000096717 SIRT1 ENSG00000149480 MTA2 H. sapiens SSL Slorth 0.969701 View
ENSG00000096717 SIRT1 ENSG00000112118 MCM3 H. sapiens SSL Slorth 0.969688 View
ENSG00000096717 SIRT1 ENSG00000187735 TCEA1 H. sapiens SSL Slorth 0.969604 View
ENSG00000096717 SIRT1 ENSG00000106462 EZH2 H. sapiens SSL Slorth 0.969585 View
ENSG00000096717 SIRT1 ENSG00000147133 TAF1 H. sapiens SSL Slorth 0.969481 View
ENSG00000096717 SIRT1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.969369 View
ENSG00000067829 IDH3G ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.969316 View
ENSG00000096717 SIRT1 ENSG00000171621 SPSB1 H. sapiens SDL Slorth 0.969208 View
ENSG00000096717 SIRT1 ENSG00000132005 RFX1 H. sapiens SDL Slorth 0.969192 View
ENSG00000096717 SIRT1 ENSG00000166501 PRKCB H. sapiens SSL Slorth 0.969159 View
ENSG00000096717 SIRT1 ENSG00000175793 SFN H. sapiens SSL Slorth 0.96915 View