NOTCH1

ENSG00000148400 - H. sapiens

Pathways

Go term Description
GO:0001047 core promoter binding
GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0004857 enzyme inhibitor activity
GO:0004872 receptor activity
GO:0005112 Notch binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0031490 chromatin DNA binding
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity

Drugs

No drugs in record

Diseases

Disease Name
T-ALL
breast
bladder
skin SCC
lung SCC
head and neck SCC

Orthologs

Gene Organism
N D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000164683 HEY1 ENSG00000148400 NOTCH1 H. sapiens SSL BioGRID 1.0 View
ENSG00000135547 HEY2 ENSG00000148400 NOTCH1 H. sapiens SSL BioGRID 1.0 View
ENSG00000100393 EP300 ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.98627 View
ENSG00000012048 BRCA1 ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.984054 View
ENSG00000132646 PCNA ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.983333 View
ENSG00000139687 RB1 ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.982266 View
ENSG00000141510 TP53 ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.981954 View
ENSG00000005339 CREBBP ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.97993 View
ENSG00000116478 HDAC1 ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.978037 View
ENSG00000100030 MAPK1 ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.977965 View
ENSG00000123374 CDK2 ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.977739 View
ENSG00000148400 NOTCH1 ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.976896 View
ENSG00000121022 COPS5 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.976032 View
ENSG00000148400 NOTCH1 ENSG00000165409 TSHR H. sapiens SDL Slorth 0.975722 View
ENSG00000082701 GSK3B ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.975577 View
ENSG00000136997 MYC ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.975544 View
ENSG00000133703 KRAS ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.975175 View
ENSG00000148400 NOTCH1 ENSG00000197299 BLM H. sapiens SSL Slorth 0.974882 View
ENSG00000132383 RPA1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.973587 View
ENSG00000148400 NOTCH1 ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.973557 View
ENSG00000113575 PPP2CA ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.973487 View
ENSG00000141027 NCOR1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.973458 View
ENSG00000082701 GSK3B ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.973291 View
ENSG00000148400 NOTCH1 ENSG00000150991 UBC H. sapiens SDL Slorth 0.973244 View
ENSG00000148400 NOTCH1 ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.973093 View
ENSG00000135486 HNRNPA1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.9729 View
ENSG00000101412 E2F1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.972861 View
ENSG00000109670 FBXW7 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.972807 View
ENSG00000134086 VHL ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.972743 View
ENSG00000148400 NOTCH1 ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.972418 View
ENSG00000101266 CSNK2A1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.972315 View
ENSG00000148400 NOTCH1 ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.972286 View
ENSG00000113575 PPP2CA ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.972199 View
ENSG00000135446 CDK4 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.972182 View
ENSG00000124762 CDKN1A ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.97194 View
ENSG00000124181 PLCG1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.971667 View
ENSG00000148400 NOTCH1 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.97164 View
ENSG00000148400 NOTCH1 ENSG00000170315 UBB H. sapiens SDL Slorth 0.971443 View
ENSG00000148400 NOTCH1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.971336 View
ENSG00000139687 RB1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.971044 View