SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000150991 UBC ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.985211 View
ENSG00000133703 KRAS ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.985151 View
ENSG00000109670 FBXW7 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.982244 View
ENSG00000175387 SMAD2 ENSG00000238134 EHMT2 H. sapiens SDL Slorth 0.981943 View
ENSG00000175387 SMAD2 ENSG00000180008 SOCS4 H. sapiens SDL Slorth 0.981633 View
ENSG00000164654 MIOS ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.981484 View
ENSG00000110048 OSBP ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.981461 View
ENSG00000157601 MX1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.981405 View
ENSG00000082146 STRADB ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.981205 View
ENSG00000175387 SMAD2 ENSG00000185386 MAPK11 H. sapiens SDL Slorth 0.980771 View
ENSG00000079335 CDC14A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.980629 View
ENSG00000149554 CHEK1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.980614 View
ENSG00000077380 DYNC1I2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979809 View
ENSG00000077935 SMC1B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979778 View
ENSG00000021574 SPAST ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979767 View
ENSG00000145734 BDP1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979744 View
ENSG00000175387 SMAD2 ENSG00000177565 TBL1XR1 H. sapiens SDL Slorth 0.979709 View
ENSG00000106346 USP42 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.97963 View
ENSG00000135486 HNRNPA1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.979614 View
ENSG00000132386 SERPINF1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979545 View
ENSG00000102317 RBM3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979504 View
ENSG00000154997 SEPT14 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979439 View
ENSG00000085449 WDFY1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979403 View
ENSG00000079156 OSBPL6 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979327 View
ENSG00000110031 LPXN ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979246 View
ENSG00000100239 PPP6R2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.97921 View
ENSG00000130703 OSBPL2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979186 View
ENSG00000012048 BRCA1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.979011 View
ENSG00000152822 GRM1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978983 View
ENSG00000102683 SGCG ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978983 View
ENSG00000113240 CLK4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978972 View
ENSG00000135446 CDK4 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.978955 View
ENSG00000116990 MYCL ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978952 View
ENSG00000129354 AP1M2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978948 View
ENSG00000153944 MSI2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978934 View
ENSG00000148248 SURF4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.97884 View
ENSG00000100372 SLC25A17 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978814 View
ENSG00000079337 RAPGEF3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978805 View
ENSG00000086619 ERO1B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978805 View
ENSG00000136014 USP44 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.978679 View