SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000148908 RGS10 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96912 View
ENSG00000142208 AKT1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969041 View
ENSG00000160193 WDR4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969022 View
ENSG00000078140 UBE2K ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.968985 View
ENSG00000137693 YAP1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.968978 View
ENSG00000172379 ARNT2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.968974 View
ENSG00000117400 MPL ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.968944 View
ENSG00000143252 SDHC ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.968944 View
ENSG00000034152 MAP2K3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.968934 View
ENSG00000172531 PPP1CA ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.968847 View
ENSG00000063244 U2AF2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.968816 View
ENSG00000132437 DDC ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.968761 View
ENSG00000138756 BMP2K ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.968695 View
ENSG00000141027 NCOR1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.968683 View
ENSG00000175387 SMAD2 ENSG00000177189 RPS6KA3 H. sapiens SDL Slorth 0.968676 View
ENSG00000165392 WRN ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.96867 View
ENSG00000175387 SMAD2 ENSG00000186908 ZDHHC17 H. sapiens SDL Slorth 0.968494 View
ENSG00000062822 POLD1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.96849 View
ENSG00000072062 PRKACA ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.968366 View
ENSG00000143776 CDC42BPA ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96833 View
ENSG00000125107 CNOT1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.968115 View
ENSG00000175387 SMAD2 ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.968048 View
ENSG00000111262 KCNA1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.968045 View
ENSG00000004897 CDC27 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.967976 View
ENSG00000136750 GAD2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967976 View
ENSG00000090889 KIF4A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967943 View
ENSG00000137166 FOXP4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967939 View
ENSG00000139998 RAB15 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967939 View
ENSG00000121022 COPS5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96786 View
ENSG00000163932 PRKCD ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.967825 View
ENSG00000175387 SMAD2 ENSG00000198561 CTNND1 H. sapiens SDL Slorth 0.967781 View
ENSG00000175387 SMAD2 ENSG00000186153 WWOX H. sapiens SDL Slorth 0.96774 View
ENSG00000154237 LRRK1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967634 View
ENSG00000175387 SMAD2 ENSG00000175745 NR2F1 H. sapiens SDL Slorth 0.967596 View
ENSG00000079999 KEAP1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.967505 View
ENSG00000137486 ARRB1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.967437 View
ENSG00000048540 LMO3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96731 View
ENSG00000070010 UFD1L ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.96731 View
ENSG00000072315 TRPC5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967249 View
ENSG00000151150 ANK3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967249 View