SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000175387 SMAD2 ENSG00000182944 EWSR1 H. sapiens SDL Slorth 0.964261 View
ENSG00000175387 SMAD2 ENSG00000189079 ARID2 H. sapiens SDL Slorth 0.964241 View
ENSG00000175387 SMAD2 ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.96424 View
ENSG00000147647 DPYS ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.964234 View
ENSG00000144644 GADL1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.964234 View
ENSG00000151746 BICD1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.964194 View
ENSG00000143847 PPFIA4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.964194 View
ENSG00000166963 MAP1A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.964194 View
ENSG00000095397 WHRN ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.964181 View
ENSG00000146232 NFKBIE ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.964171 View
ENSG00000048462 TNFRSF17 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.964067 View
ENSG00000157106 SMG1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.964014 View
ENSG00000118900 UBN1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.964003 View
ENSG00000116478 HDAC1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.963991 View
ENSG00000058404 CAMK2B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.963978 View
ENSG00000175387 SMAD2 ENSG00000196911 KPNA5 H. sapiens SDL Slorth 0.963976 View
ENSG00000108947 EFNB3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.963895 View
ENSG00000175387 SMAD2 ENSG00000198836 OPA1 H. sapiens SDL Slorth 0.963865 View
ENSG00000108953 YWHAE ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.963854 View
ENSG00000160360 GPSM1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.963818 View
ENSG00000114554 PLXNA1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.963772 View
ENSG00000085511 MAP3K4 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.963728 View
ENSG00000080815 PSEN1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.963602 View
ENSG00000175387 SMAD2 ENSG00000183570 PCBP3 H. sapiens SDL Slorth 0.963557 View
ENSG00000143420 ENSA ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.963437 View
ENSG00000170365 SMAD1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.963423 View
ENSG00000156345 CDK20 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.963409 View
ENSG00000175387 SMAD2 ENSG00000198399 ITSN2 H. sapiens SDL Slorth 0.96335 View
ENSG00000175387 SMAD2 ENSG00000175832 ETV4 H. sapiens SDL Slorth 0.96327 View
ENSG00000150093 ITGB1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.963216 View
ENSG00000105173 CCNE1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.963132 View
ENSG00000175387 SMAD2 ENSG00000198742 SMURF1 H. sapiens SDL Slorth 0.963109 View
ENSG00000145331 TRMT10A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.963067 View
ENSG00000101412 E2F1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.963047 View
ENSG00000126368 NR1D1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.962937 View
ENSG00000163536 SERPINI1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96292 View
ENSG00000152578 GRIA4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96292 View
ENSG00000175387 SMAD2 ENSG00000225830 ERCC6 H. sapiens SDL Slorth 0.962914 View
ENSG00000105810 CDK6 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.962844 View
ENSG00000131747 TOP2A ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.962805 View