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SMAD2 - ERCC6
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
SMAD2
ENSG00000175387
colorectal carcinoma
hepatocellular carcinoma
No drugs in record
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transforming growth factor beta receptor binding
protein binding
transcription factor binding
phosphatase binding
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
ubiquitin protein ligase binding
activating transcription factor binding
type I transforming growth factor beta receptor binding
enhancer binding
protein homodimerization activity
SMAD binding
metal ion binding
protein heterodimerization activity
co-SMAD binding
I-SMAD binding
R-SMAD binding
DNA binding
sma-3 (C. elegans)
sma-2 (C. elegans)
ERCC6
ENSG00000225830
No diseases in record
No drugs in record
DNA binding
chromatin binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
protein tyrosine kinase activator activity
protein complex binding
protein N-terminus binding
DNA helicase activity
RAD26 (S. cerevisiae)