SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135312 HTR1B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967249 View
ENSG00000072315 TRPC5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967249 View
ENSG00000029639 TFB1M ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967228 View
ENSG00000175387 SMAD2 ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.967207 View
ENSG00000168418 KCNG4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.9672 View
ENSG00000063660 GPC1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.9672 View
ENSG00000041982 TNC ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.9672 View
ENSG00000175387 SMAD2 ENSG00000180176 TH H. sapiens SDL Slorth 0.967166 View
ENSG00000175387 SMAD2 ENSG00000220205 VAMP2 H. sapiens SDL Slorth 0.967159 View
ENSG00000143256 PFDN2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967093 View
ENSG00000004975 DVL2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.967079 View
ENSG00000169047 IRS1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.96702 View
ENSG00000175387 SMAD2 ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.967008 View
ENSG00000167550 RHEBL1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96693 View
ENSG00000005339 CREBBP ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966895 View
ENSG00000102781 KATNAL1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96689 View
ENSG00000075340 ADD2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966798 View
ENSG00000175387 SMAD2 ENSG00000198873 GRK5 H. sapiens SDL Slorth 0.966789 View
ENSG00000175387 SMAD2 ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.966783 View
ENSG00000125967 NECAB3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966781 View
ENSG00000005882 PDK2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966781 View
ENSG00000111540 RAB5B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96675 View
ENSG00000061918 GUCY1B3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966689 View
ENSG00000137942 FNBP1L ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966561 View
ENSG00000108830 RND2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966527 View
ENSG00000115221 ITGB6 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966508 View
ENSG00000175387 SMAD2 ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.966488 View
ENSG00000165832 TRUB1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966482 View
ENSG00000175387 SMAD2 ENSG00000175592 FOSL1 H. sapiens SDL Slorth 0.966434 View
ENSG00000078114 NEBL ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96642 View
ENSG00000166947 EPB42 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96642 View
ENSG00000175387 SMAD2 ENSG00000244687 UBE2V1 H. sapiens SDL Slorth 0.966339 View
ENSG00000114423 CBLB ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.966338 View
ENSG00000105737 GRIK5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966312 View
ENSG00000163394 CCKAR ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966312 View
ENSG00000100228 RAB36 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966312 View
ENSG00000085185 BCORL1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966312 View
ENSG00000140199 SLC12A6 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966312 View
ENSG00000138594 TMOD3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.966312 View
ENSG00000175387 SMAD2 ENSG00000198677 TTC37 H. sapiens SDL Slorth 0.966128 View