SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097046 CDC7 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.97443 View
ENSG00000137825 ITPKA ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.974387 View
ENSG00000143033 MTF2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.974354 View
ENSG00000175387 SMAD2 ENSG00000188130 MAPK12 H. sapiens SDL Slorth 0.97433 View
ENSG00000134057 CCNB1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.974323 View
ENSG00000101349 PAK5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.974238 View
ENSG00000101146 RAE1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.974196 View
ENSG00000144668 ITGA9 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.974173 View
ENSG00000143344 RGL1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.974145 View
ENSG00000001626 CFTR ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.974144 View
ENSG00000136237 RAPGEF5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.974127 View
ENSG00000004700 RECQL ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.974059 View
ENSG00000101972 STAG2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.974032 View
ENSG00000004848 ARX ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973889 View
ENSG00000163485 ADORA1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973848 View
ENSG00000159496 RGL4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973848 View
ENSG00000175387 SMAD2 ENSG00000184675 AMER1 H. sapiens SDL Slorth 0.973803 View
ENSG00000123094 RASSF8 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973624 View
ENSG00000134371 CDC73 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973486 View
ENSG00000171634 BPTF ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973407 View
ENSG00000112679 DUSP22 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973336 View
ENSG00000105204 DYRK1B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973326 View
ENSG00000161940 BCL6B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973265 View
ENSG00000175387 SMAD2 ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.973251 View
ENSG00000101134 DOK5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973242 View
ENSG00000170577 SIX2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973241 View
ENSG00000111218 PRMT8 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.973137 View
ENSG00000135018 UBQLN1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.972988 View
ENSG00000119048 UBE2B ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.972955 View
ENSG00000135723 FHOD1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.97293 View
ENSG00000168283 BMI1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.972921 View
ENSG00000082898 XPO1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.972892 View
ENSG00000140455 USP3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.972888 View
ENSG00000101213 PTK6 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.972772 View
ENSG00000175387 SMAD2 ENSG00000175793 SFN H. sapiens SDL Slorth 0.972674 View
ENSG00000175387 SMAD2 ENSG00000198517 MAFK H. sapiens SDL Slorth 0.97266 View
ENSG00000126261 UBA2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.972613 View
ENSG00000092201 SUPT16H ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.972534 View
ENSG00000110092 CCND1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.97245 View
ENSG00000163435 ELF3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.972433 View