SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000127511 SIN3B ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970634 View
ENSG00000169139 UBE2V2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970627 View
ENSG00000072736 NFATC3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970562 View
ENSG00000128271 ADORA2A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970503 View
ENSG00000041353 RAB27B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970503 View
ENSG00000171126 KCNG3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970503 View
ENSG00000125810 CD93 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970503 View
ENSG00000058729 RIOK2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970433 View
ENSG00000164885 CDK5 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970388 View
ENSG00000103126 AXIN1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970318 View
ENSG00000173404 INSM1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970306 View
ENSG00000148200 NR6A1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970275 View
ENSG00000082701 GSK3B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970218 View
ENSG00000164109 MAD2L1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970111 View
ENSG00000175387 SMAD2 ENSG00000198373 WWP2 H. sapiens SDL Slorth 0.970105 View
ENSG00000125656 CLPP ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.970074 View
ENSG00000141480 ARRB2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.970064 View
ENSG00000132466 ANKRD17 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969941 View
ENSG00000104365 IKBKB ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969889 View
ENSG00000162231 NXF1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.969884 View
ENSG00000175387 SMAD2 ENSG00000196218 RYR1 H. sapiens SDL Slorth 0.969717 View
ENSG00000117707 PROX1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969687 View
ENSG00000175387 SMAD2 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.969682 View
ENSG00000121879 PIK3CA ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.969668 View
ENSG00000087586 AURKA ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.969634 View
ENSG00000005007 UPF1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.969624 View
ENSG00000134982 APC ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.969613 View
ENSG00000110148 CCKBR ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969599 View
ENSG00000167986 DDB1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.969566 View
ENSG00000154582 TCEB1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.969565 View
ENSG00000087510 TFAP2C ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969511 View
ENSG00000171016 PYGO1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969461 View
ENSG00000169435 RASSF6 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969391 View
ENSG00000175387 SMAD2 ENSG00000198176 TFDP1 H. sapiens SDL Slorth 0.969319 View
ENSG00000175387 SMAD2 ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.969309 View
ENSG00000160145 KALRN ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969299 View
ENSG00000102054 RBBP7 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.969253 View
ENSG00000087274 ADD1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969167 View
ENSG00000074181 NOTCH3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.969163 View
ENSG00000122406 RPL5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.96913 View