PIK3CA

ENSG00000121879 - H. sapiens

Pathways

Go term Description
GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0030295 protein kinase activator activity
GO:0035004 phosphatidylinositol 3-kinase activity
GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0043560 insulin receptor substrate binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

No drugs in record

Diseases

Disease Name
colorectal
gastric
glioblastoma
breast

Orthologs

Gene Organism
VPS34 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000121879 PIK3CA ENSG00000032389 TSSC1 H. sapiens SSL BioGRID 1.0 View
ENSG00000157764 BRAF ENSG00000121879 PIK3CA H. sapiens SSL BioGRID 1.0 View
ENSG00000008118 CAMK1G ENSG00000121879 PIK3CA H. sapiens SSL BioGRID 1.0 View
ENSG00000136807 CDK9 ENSG00000121879 PIK3CA H. sapiens SSL BioGRID 1.0 View
ENSG00000149554 CHEK1 ENSG00000121879 PIK3CA H. sapiens SSL BioGRID 1.0 View
ENSG00000094631 HDAC6 ENSG00000121879 PIK3CA H. sapiens SSL BioGRID 1.0 View
ENSG00000133703 KRAS ENSG00000121879 PIK3CA H. sapiens SSL BioGRID 1.0 View
ENSG00000121879 PIK3CA ENSG00000154229 PRKCA H. sapiens SSL BioGRID 1.0 View
ENSG00000121879 PIK3CA ENSG00000171848 RRM2 H. sapiens SSL BioGRID 1.0 View
ENSG00000110395 CBL ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.982724 View
ENSG00000116478 HDAC1 ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.980119 View
ENSG00000121879 PIK3CA ENSG00000150991 UBC H. sapiens SDL Slorth 0.978487 View
ENSG00000121879 PIK3CA ENSG00000132170 PPARG H. sapiens SSL Slorth 0.97518 View
ENSG00000012048 BRCA1 ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.974539 View
ENSG00000080824 HSP90AA1 ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.974216 View
ENSG00000121879 PIK3CA ENSG00000134086 VHL H. sapiens SSL Slorth 0.973385 View
ENSG00000091831 ESR1 ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.972994 View
ENSG00000121879 PIK3CA ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.972641 View
ENSG00000100393 EP300 ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.971318 View
ENSG00000121879 PIK3CA ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.970976 View
ENSG00000121879 PIK3CA ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.97084 View
ENSG00000121879 PIK3CA ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.970755 View
ENSG00000121879 PIK3CA ENSG00000156970 BUB1B H. sapiens SSL Slorth 0.970487 View
ENSG00000121879 PIK3CA ENSG00000170345 FOS H. sapiens SSL Slorth 0.970081 View
ENSG00000121879 PIK3CA ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.970008 View
ENSG00000121879 PIK3CA ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.969838 View
ENSG00000121879 PIK3CA ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.969668 View
ENSG00000121879 PIK3CA ENSG00000186868 MAPT H. sapiens SSL Slorth 0.969527 View
ENSG00000121879 PIK3CA ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.969472 View
ENSG00000121879 PIK3CA ENSG00000145604 SKP2 H. sapiens SSL Slorth 0.969341 View
ENSG00000121879 PIK3CA ENSG00000166851 PLK1 H. sapiens SSL Slorth 0.968856 View
ENSG00000121879 PIK3CA ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.968391 View
ENSG00000121879 PIK3CA ENSG00000129559 NEDD8 H. sapiens SSL Slorth 0.96837 View
ENSG00000121879 PIK3CA ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.968259 View
ENSG00000121879 PIK3CA ENSG00000134057 CCNB1 H. sapiens SSL Slorth 0.968172 View
ENSG00000121879 PIK3CA ENSG00000135018 UBQLN1 H. sapiens SSL Slorth 0.967318 View
ENSG00000121879 PIK3CA ENSG00000134982 APC H. sapiens SSL Slorth 0.967282 View
ENSG00000121879 PIK3CA ENSG00000134308 YWHAQ H. sapiens SSL Slorth 0.966769 View
ENSG00000121879 PIK3CA ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.966569 View
ENSG00000121879 PIK3CA ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.966244 View