PIK3CA

ENSG00000121879 - H. sapiens

Pathways

Go term Description
GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0030295 protein kinase activator activity
GO:0035004 phosphatidylinositol 3-kinase activity
GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0043560 insulin receptor substrate binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

No drugs in record

Diseases

Disease Name
colorectal
gastric
glioblastoma
breast

Orthologs

Gene Organism
VPS34 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000121879 PIK3CA ENSG00000198742 SMURF1 H. sapiens SSL Slorth 0.95864 View
ENSG00000121879 PIK3CA ENSG00000170027 YWHAG H. sapiens SSL Slorth 0.95854 View
ENSG00000121879 PIK3CA ENSG00000162231 NXF1 H. sapiens SSL Slorth 0.958402 View
ENSG00000121879 PIK3CA ENSG00000136518 ACTL6A H. sapiens SSL Slorth 0.958248 View
ENSG00000121879 PIK3CA ENSG00000140464 PML H. sapiens SSL Slorth 0.957501 View
ENSG00000121879 PIK3CA ENSG00000128052 KDR H. sapiens SSL Slorth 0.957321 View
ENSG00000050820 BCAR1 ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.956896 View
ENSG00000121879 PIK3CA ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.956497 View
ENSG00000121879 PIK3CA ENSG00000151247 EIF4E H. sapiens SSL Slorth 0.956482 View
ENSG00000121879 PIK3CA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.956219 View
ENSG00000121879 PIK3CA ENSG00000157106 SMG1 H. sapiens SSL Slorth 0.955335 View
ENSG00000100030 MAPK1 ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.955076 View
ENSG00000121879 PIK3CA ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.955009 View
ENSG00000121879 PIK3CA ENSG00000186716 BCR H. sapiens SSL Slorth 0.954957 View
ENSG00000121879 PIK3CA ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.954394 View
ENSG00000121879 PIK3CA ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.954363 View
ENSG00000121879 PIK3CA ENSG00000166226 CCT2 H. sapiens SSL Slorth 0.954141 View
ENSG00000121879 PIK3CA ENSG00000164109 MAD2L1 H. sapiens SSL Slorth 0.954106 View
ENSG00000121879 PIK3CA ENSG00000182866 LCK H. sapiens SSL Slorth 0.95362 View
ENSG00000010810 FYN ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.953427 View
ENSG00000121879 PIK3CA ENSG00000163932 PRKCD H. sapiens SSL Slorth 0.953133 View
ENSG00000121879 PIK3CA ENSG00000148606 POLR3A H. sapiens SSL Slorth 0.951813 View
ENSG00000121879 PIK3CA ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.951629 View
ENSG00000121879 PIK3CA ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.951096 View
ENSG00000121879 PIK3CA ENSG00000135341 MAP3K7 H. sapiens SSL Slorth 0.950945 View
ENSG00000121879 PIK3CA ENSG00000146648 EGFR H. sapiens SDL Slorth 0.950471 View
ENSG00000121879 PIK3CA ENSG00000150753 CCT5 H. sapiens SSL Slorth 0.950368 View
ENSG00000121879 PIK3CA ENSG00000164305 CASP3 H. sapiens SSL Slorth 0.950358 View
ENSG00000121879 PIK3CA ENSG00000154582 TCEB1 H. sapiens SSL Slorth 0.95007 View
ENSG00000121879 PIK3CA ENSG00000171105 INSR H. sapiens SSL Slorth 0.949697 View
ENSG00000121879 PIK3CA ENSG00000165025 SYK H. sapiens SSL Slorth 0.949695 View
ENSG00000121879 PIK3CA ENSG00000213341 CHUK H. sapiens SSL Slorth 0.949166 View
ENSG00000121879 PIK3CA ENSG00000166913 YWHAB H. sapiens SSL Slorth 0.949061 View
ENSG00000089159 PXN ENSG00000121879 PIK3CA H. sapiens SDL Slorth 0.94878 View
ENSG00000121879 PIK3CA ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.948693 View
ENSG00000121879 PIK3CA ENSG00000124762 CDKN1A H. sapiens SSL Slorth 0.948473 View
ENSG00000121879 PIK3CA ENSG00000169398 PTK2 H. sapiens SSL Slorth 0.948278 View
ENSG00000121879 PIK3CA ENSG00000124181 PLCG1 H. sapiens SSL Slorth 0.947897 View
ENSG00000121879 PIK3CA ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.947599 View
ENSG00000121879 PIK3CA ENSG00000141564 RPTOR H. sapiens SSL Slorth 0.947476 View