FEN1

ENSG00000168496 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0008309 double-stranded DNA exodeoxyribonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0048256 flap endonuclease activity
GO:0004518 nuclease activity

Drugs

No drugs in record

Diseases

Disease Name
breast cancer

Orthologs

Gene Organism
RAD27 S. cerevisiae
crn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000168496 FEN1 ENSG00000143799 PARP1 H. sapiens SSL BioGRID 1.0 View
ENSG00000168496 FEN1 ENSG00000129484 PARP2 H. sapiens SSL BioGRID 1.0 View
ENSG00000168496 FEN1 ENSG00000177889 UBE2N H. sapiens SSL BioGRID 1.0 View
ENSG00000149311 ATM ENSG00000168496 FEN1 H. sapiens SSL BioGRID 1.0 View
ENSG00000168496 FEN1 ENSG00000071794 HLTF H. sapiens SSL BioGRID 1.0 View
ENSG00000132646 PCNA ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.989268 View
ENSG00000166949 SMAD3 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.988848 View
ENSG00000150991 UBC ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.988756 View
ENSG00000116478 HDAC1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.98639 View
ENSG00000100393 EP300 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.984242 View
ENSG00000162385 MAGOH ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.98226 View
ENSG00000123374 CDK2 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.980215 View
ENSG00000142208 AKT1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.980091 View
ENSG00000166949 SMAD3 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.979952 View
ENSG00000082701 GSK3B ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.97987 View
ENSG00000005339 CREBBP ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.979723 View
ENSG00000121022 COPS5 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.979518 View
ENSG00000141736 ERBB2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.979408 View
ENSG00000136997 MYC ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.979068 View
ENSG00000134086 VHL ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.979019 View
ENSG00000103275 UBE2I ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.978812 View
ENSG00000113575 PPP2CA ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.97836 View
ENSG00000101266 CSNK2A1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.978334 View
ENSG00000109670 FBXW7 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.978051 View
ENSG00000116030 SUMO1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.978023 View
ENSG00000112062 MAPK14 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.977882 View
ENSG00000130726 TRIM28 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.977751 View
ENSG00000133703 KRAS ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.977698 View
ENSG00000010810 FYN ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.97744 View
ENSG00000123374 CDK2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.9774 View
ENSG00000012048 BRCA1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.97738 View
ENSG00000139687 RB1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.977144 View
ENSG00000141646 SMAD4 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.977134 View
ENSG00000103275 UBE2I ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.977057 View
ENSG00000142208 AKT1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.9769 View
ENSG00000149554 CHEK1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.976386 View
ENSG00000110092 CCND1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.976232 View
ENSG00000100030 MAPK1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.976191 View
ENSG00000101412 E2F1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.97619 View
ENSG00000141027 NCOR1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.976169 View