FEN1

ENSG00000168496 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0008309 double-stranded DNA exodeoxyribonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0048256 flap endonuclease activity
GO:0004518 nuclease activity

Drugs

No drugs in record

Diseases

Disease Name
breast cancer

Orthologs

Gene Organism
RAD27 S. cerevisiae
crn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000139687 RB1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.975823 View
ENSG00000132383 RPA1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.975542 View
ENSG00000164305 CASP3 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.975499 View
ENSG00000124762 CDKN1A ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.975217 View
ENSG00000164924 YWHAZ ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.975123 View
ENSG00000141510 TP53 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.974783 View
ENSG00000149311 ATM ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.974638 View
ENSG00000096717 SIRT1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.974483 View
ENSG00000005339 CREBBP ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.97376 View
ENSG00000012048 BRCA1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.973595 View
ENSG00000101266 CSNK2A1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.973293 View
ENSG00000135446 CDK4 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.973257 View
ENSG00000101966 XIAP ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.973198 View
ENSG00000168148 HIST3H3 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.973137 View
ENSG00000112592 TBP ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.972902 View
ENSG00000111276 CDKN1B ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.972845 View
ENSG00000132155 RAF1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.972633 View
ENSG00000113721 PDGFRB ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.972603 View
ENSG00000131759 RARA ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.972583 View
ENSG00000097007 ABL1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.972504 View
ENSG00000082701 GSK3B ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.972464 View
ENSG00000102882 MAPK3 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.972444 View
ENSG00000149554 CHEK1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.972394 View
ENSG00000164305 CASP3 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.972185 View
ENSG00000117399 CDC20 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.971958 View
ENSG00000135486 HNRNPA1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.971932 View
ENSG00000080824 HSP90AA1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.971916 View
ENSG00000165392 WRN ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.971773 View
ENSG00000072401 UBE2D1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.971769 View
ENSG00000110395 CBL ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.971572 View
ENSG00000124762 CDKN1A ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.971085 View
ENSG00000069869 NEDD4 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.970988 View
ENSG00000004700 RECQL ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.970805 View
ENSG00000094804 CDC6 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.970804 View
ENSG00000136997 MYC ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.970795 View
ENSG00000159692 CTBP1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.970651 View
ENSG00000135341 MAP3K7 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.970636 View
ENSG00000136807 CDK9 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.970344 View
ENSG00000164924 YWHAZ ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.969798 View
ENSG00000132383 RPA1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.969584 View