FEN1

ENSG00000168496 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0008309 double-stranded DNA exodeoxyribonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0048256 flap endonuclease activity
GO:0004518 nuclease activity

Drugs

No drugs in record

Diseases

Disease Name
breast cancer

Orthologs

Gene Organism
RAD27 S. cerevisiae
crn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000167986 DDB1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.964029 View
ENSG00000073111 MCM2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.963776 View
ENSG00000087586 AURKA ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.963747 View
ENSG00000168283 BMI1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.963736 View
ENSG00000145386 CCNA2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.963728 View
ENSG00000132155 RAF1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.963374 View
ENSG00000165119 HNRNPK ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.963354 View
ENSG00000119048 UBE2B ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.963312 View
ENSG00000148400 NOTCH1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.963297 View
ENSG00000108953 YWHAE ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.963127 View
ENSG00000078747 ITCH ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.962475 View
ENSG00000124181 PLCG1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.962407 View
ENSG00000005007 UPF1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.962251 View
ENSG00000138376 BARD1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.961914 View
ENSG00000154229 PRKCA ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.961873 View
ENSG00000104738 MCM4 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.961848 View
ENSG00000091831 ESR1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.961597 View
ENSG00000091831 ESR1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.961578 View
ENSG00000113558 SKP1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.961368 View
ENSG00000145604 SKP2 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.96128 View
ENSG00000134308 YWHAQ ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.961221 View
ENSG00000146648 EGFR ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.960968 View
ENSG00000127022 CANX ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.960738 View
ENSG00000167658 EEF2 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.960598 View
ENSG00000112118 MCM3 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.960501 View
ENSG00000110092 CCND1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.960403 View
ENSG00000149273 RPS3 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.960273 View
ENSG00000070950 RAD18 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.960181 View
ENSG00000105568 PPP2R1A ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.959791 View
ENSG00000001626 CFTR ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.959709 View
ENSG00000065559 MAP2K4 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.959629 View
ENSG00000070010 UFD1L ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.959559 View
ENSG00000168496 FEN1 ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.959163 View
ENSG00000101868 POLA1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.959012 View
ENSG00000140992 PDPK1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.958986 View
ENSG00000136518 ACTL6A ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.958954 View
ENSG00000101868 POLA1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.958923 View
ENSG00000108671 PSMD11 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.95883 View
ENSG00000168496 FEN1 ENSG00000176720 BOK H. sapiens SDL Slorth 0.958545 View
ENSG00000165280 VCP ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.958251 View