NOTCH1 - FEN1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
FEN1	ENSG00000168496	breast cancer	No drugs in record	magnesium ion binding DNA binding damaged DNA binding double-stranded DNA binding endonuclease activity RNA-DNA hybrid ribonuclease activity exonuclease activity protein binding double-stranded DNA exodeoxyribonuclease activity 5'-3' exonuclease activity 5'-flap endonuclease activity flap endonuclease activity nuclease activity	RAD27 (S. cerevisiae) crn-1 (C. elegans)