FEN1

ENSG00000168496 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0008309 double-stranded DNA exodeoxyribonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0048256 flap endonuclease activity
GO:0004518 nuclease activity

Drugs

No drugs in record

Diseases

Disease Name
breast cancer

Orthologs

Gene Organism
RAD27 S. cerevisiae
crn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000160691 SHC1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.948579 View
ENSG00000132646 PCNA ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.948335 View
ENSG00000168496 FEN1 ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.948325 View
ENSG00000010810 FYN ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.948222 View
ENSG00000075624 ACTB ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.948052 View
ENSG00000104365 IKBKB ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.948029 View
ENSG00000140464 PML ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.947952 View
ENSG00000134853 PDGFRA ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.947892 View
ENSG00000136238 RAC1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.9478 View
ENSG00000168496 FEN1 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.947751 View
ENSG00000093009 CDC45 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.947659 View
ENSG00000121481 RNF2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.947591 View
ENSG00000101665 SMAD7 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.947448 View
ENSG00000119541 VPS4B ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.947379 View
ENSG00000062822 POLD1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.947147 View
ENSG00000073111 MCM2 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.947007 View
ENSG00000062822 POLD1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.946656 View
ENSG00000112592 TBP ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.946591 View
ENSG00000114423 CBLB ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.94612 View
ENSG00000166508 MCM7 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.945933 View
ENSG00000168496 FEN1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.945925 View
ENSG00000154473 BUB3 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.945793 View
ENSG00000168496 FEN1 ENSG00000170345 FOS H. sapiens SSL Slorth 0.945754 View
ENSG00000168496 FEN1 ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.94562 View
ENSG00000168496 FEN1 ENSG00000173404 INSM1 H. sapiens SDL Slorth 0.945616 View
ENSG00000110395 CBL ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.945607 View
ENSG00000105325 FZR1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.945549 View
ENSG00000168496 FEN1 ENSG00000169398 PTK2 H. sapiens SSL Slorth 0.945534 View
ENSG00000080824 HSP90AA1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.945507 View
ENSG00000080503 SMARCA2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.945307 View
ENSG00000168496 FEN1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.945146 View
ENSG00000168496 FEN1 ENSG00000184937 WT1 H. sapiens SDL Slorth 0.945078 View
ENSG00000168496 FEN1 ENSG00000175792 RUVBL1 H. sapiens SSL Slorth 0.944824 View
ENSG00000147536 GINS4 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.944653 View
ENSG00000166501 PRKCB ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.944605 View
ENSG00000157106 SMG1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.944179 View
ENSG00000136936 XPA ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.944062 View
ENSG00000168496 FEN1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.944008 View
ENSG00000072062 PRKACA ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.94398 View
ENSG00000168496 FEN1 ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.943977 View