LYN

ENSG00000254087 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005102 receptor binding
GO:0005161 platelet-derived growth factor receptor binding
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017124 SH3 domain binding
GO:0031625 ubiquitin protein ligase binding
GO:0043015 gamma-tubulin binding
GO:0043208 glycosphingolipid binding
GO:0044325 ion channel binding
GO:0051219 phosphoprotein binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Src64B D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132646 PCNA ENSG00000254087 LYN H. sapiens SDL Slorth 0.991544 View
ENSG00000005339 CREBBP ENSG00000254087 LYN H. sapiens SDL Slorth 0.990125 View
ENSG00000100393 EP300 ENSG00000254087 LYN H. sapiens SDL Slorth 0.989806 View
ENSG00000185591 SP1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.989284 View
ENSG00000012048 BRCA1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.987647 View
ENSG00000116478 HDAC1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.986185 View
ENSG00000141510 TP53 ENSG00000254087 LYN H. sapiens SDL Slorth 0.984386 View
ENSG00000177606 JUN ENSG00000254087 LYN H. sapiens SDL Slorth 0.983829 View
ENSG00000124181 PLCG1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.981755 View
ENSG00000139687 RB1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.981749 View
ENSG00000134086 VHL ENSG00000254087 LYN H. sapiens SSL Slorth 0.981033 View
ENSG00000142208 AKT1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.980767 View
ENSG00000149554 CHEK1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.980413 View
ENSG00000150991 UBC ENSG00000254087 LYN H. sapiens SDL Slorth 0.980159 View
ENSG00000101266 CSNK2A1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.979786 View
ENSG00000173039 RELA ENSG00000254087 LYN H. sapiens SDL Slorth 0.979557 View
ENSG00000172977 KAT5 ENSG00000254087 LYN H. sapiens SSL Slorth 0.978858 View
ENSG00000121022 COPS5 ENSG00000254087 LYN H. sapiens SSL Slorth 0.978458 View
ENSG00000162385 MAGOH ENSG00000254087 LYN H. sapiens SDL Slorth 0.97844 View
ENSG00000196591 HDAC2 ENSG00000254087 LYN H. sapiens SDL Slorth 0.977956 View
ENSG00000166949 SMAD3 ENSG00000254087 LYN H. sapiens SDL Slorth 0.977594 View
ENSG00000135446 CDK4 ENSG00000254087 LYN H. sapiens SSL Slorth 0.976741 View
ENSG00000103275 UBE2I ENSG00000254087 LYN H. sapiens SDL Slorth 0.976716 View
ENSG00000091831 ESR1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.97625 View
ENSG00000171791 BCL2 ENSG00000254087 LYN H. sapiens SSL Slorth 0.975973 View
ENSG00000197299 BLM ENSG00000254087 LYN H. sapiens SSL Slorth 0.97581 View
ENSG00000080824 HSP90AA1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.975328 View
ENSG00000096717 SIRT1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.975204 View
ENSG00000196591 HDAC2 ENSG00000254087 LYN H. sapiens SSL Slorth 0.975028 View
ENSG00000146648 EGFR ENSG00000254087 LYN H. sapiens SDL Slorth 0.974749 View
ENSG00000101266 CSNK2A1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.974739 View
ENSG00000142208 AKT1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.974703 View
ENSG00000164305 CASP3 ENSG00000254087 LYN H. sapiens SSL Slorth 0.974548 View
ENSG00000112062 MAPK14 ENSG00000254087 LYN H. sapiens SSL Slorth 0.974489 View
ENSG00000112592 TBP ENSG00000254087 LYN H. sapiens SSL Slorth 0.974373 View
ENSG00000188486 H2AFX ENSG00000254087 LYN H. sapiens SSL Slorth 0.974286 View
ENSG00000130939 UBE4B ENSG00000254087 LYN H. sapiens SSL Slorth 0.974286 View
ENSG00000124762 CDKN1A ENSG00000254087 LYN H. sapiens SDL Slorth 0.974127 View
ENSG00000005339 CREBBP ENSG00000254087 LYN H. sapiens SSL Slorth 0.974123 View
ENSG00000113575 PPP2CA ENSG00000254087 LYN H. sapiens SSL Slorth 0.974116 View