LYN

ENSG00000254087 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005102 receptor binding
GO:0005161 platelet-derived growth factor receptor binding
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017124 SH3 domain binding
GO:0031625 ubiquitin protein ligase binding
GO:0043015 gamma-tubulin binding
GO:0043208 glycosphingolipid binding
GO:0044325 ion channel binding
GO:0051219 phosphoprotein binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Src64B D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000007908 SELE ENSG00000254087 LYN H. sapiens SDL Slorth 0.955433 View
ENSG00000077380 DYNC1I2 ENSG00000254087 LYN H. sapiens SDL Slorth 0.955408 View
ENSG00000109971 HSPA8 ENSG00000254087 LYN H. sapiens SSL Slorth 0.955384 View
ENSG00000184900 SUMO3 ENSG00000254087 LYN H. sapiens SSL Slorth 0.955069 View
ENSG00000177889 UBE2N ENSG00000254087 LYN H. sapiens SSL Slorth 0.955055 View
ENSG00000149136 SSRP1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.95498 View
ENSG00000111875 ASF1A ENSG00000254087 LYN H. sapiens SSL Slorth 0.954972 View
ENSG00000198668 CALM1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.954892 View
ENSG00000175104 TRAF6 ENSG00000254087 LYN H. sapiens SDL Slorth 0.954858 View
ENSG00000091831 ESR1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.954724 View
ENSG00000169139 UBE2V2 ENSG00000254087 LYN H. sapiens SSL Slorth 0.954661 View
ENSG00000102996 MMP15 ENSG00000254087 LYN H. sapiens SDL Slorth 0.954489 View
ENSG00000123374 CDK2 ENSG00000254087 LYN H. sapiens SDL Slorth 0.954432 View
ENSG00000143847 PPFIA4 ENSG00000254087 LYN H. sapiens SDL Slorth 0.954247 View
ENSG00000132964 CDK8 ENSG00000254087 LYN H. sapiens SSL Slorth 0.953969 View
ENSG00000166167 BTRC ENSG00000254087 LYN H. sapiens SSL Slorth 0.953945 View
ENSG00000079999 KEAP1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.953754 View
ENSG00000102683 SGCG ENSG00000254087 LYN H. sapiens SDL Slorth 0.953562 View
ENSG00000157601 MX1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.95336 View
ENSG00000136238 RAC1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.953201 View
ENSG00000141027 NCOR1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.953025 View
ENSG00000079134 THOC1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.953002 View
ENSG00000060069 CTDP1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.952928 View
ENSG00000140564 FURIN ENSG00000254087 LYN H. sapiens SDL Slorth 0.952926 View
ENSG00000151247 EIF4E ENSG00000254087 LYN H. sapiens SSL Slorth 0.95291 View
ENSG00000136875 PRPF4 ENSG00000254087 LYN H. sapiens SSL Slorth 0.952844 View
ENSG00000129559 NEDD8 ENSG00000254087 LYN H. sapiens SSL Slorth 0.952765 View
ENSG00000180900 SCRIB ENSG00000254087 LYN H. sapiens SDL Slorth 0.952696 View
ENSG00000149311 ATM ENSG00000254087 LYN H. sapiens SSL Slorth 0.952566 View
ENSG00000178568 ERBB4 ENSG00000254087 LYN H. sapiens SSL Slorth 0.952541 View
ENSG00000136628 EPRS ENSG00000254087 LYN H. sapiens SSL Slorth 0.952462 View
ENSG00000093009 CDC45 ENSG00000254087 LYN H. sapiens SSL Slorth 0.95244 View
ENSG00000146094 DOK3 ENSG00000254087 LYN H. sapiens SDL Slorth 0.952395 View
ENSG00000105810 CDK6 ENSG00000254087 LYN H. sapiens SSL Slorth 0.952213 View
ENSG00000160193 WDR4 ENSG00000254087 LYN H. sapiens SDL Slorth 0.952211 View
ENSG00000188612 SUMO2 ENSG00000254087 LYN H. sapiens SDL Slorth 0.952146 View
ENSG00000196470 SIAH1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.952109 View
ENSG00000085449 WDFY1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.951951 View
ENSG00000078747 ITCH ENSG00000254087 LYN H. sapiens SSL Slorth 0.95191 View
ENSG00000165280 VCP ENSG00000254087 LYN H. sapiens SSL Slorth 0.951767 View