LYN

ENSG00000254087 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005102 receptor binding
GO:0005161 platelet-derived growth factor receptor binding
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017124 SH3 domain binding
GO:0031625 ubiquitin protein ligase binding
GO:0043015 gamma-tubulin binding
GO:0043208 glycosphingolipid binding
GO:0044325 ion channel binding
GO:0051219 phosphoprotein binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Src64B D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141968 VAV1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.949351 View
ENSG00000115904 SOS1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.949302 View
ENSG00000176894 PXMP2 ENSG00000254087 LYN H. sapiens SDL Slorth 0.949275 View
ENSG00000150753 CCT5 ENSG00000254087 LYN H. sapiens SSL Slorth 0.949258 View
ENSG00000127586 CHTF18 ENSG00000254087 LYN H. sapiens SSL Slorth 0.949171 View
ENSG00000179295 PTPN11 ENSG00000254087 LYN H. sapiens SDL Slorth 0.9491 View
ENSG00000136238 RAC1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.949039 View
ENSG00000072518 MARK2 ENSG00000254087 LYN H. sapiens SSL Slorth 0.949008 View
ENSG00000067560 RHOA ENSG00000254087 LYN H. sapiens SSL Slorth 0.948976 View
ENSG00000131508 UBE2D2 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948949 View
ENSG00000141968 VAV1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948899 View
ENSG00000136807 CDK9 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948806 View
ENSG00000055332 EIF2AK2 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948788 View
ENSG00000074319 TSG101 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948751 View
ENSG00000154473 BUB3 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948685 View
ENSG00000187682 ERAS ENSG00000254087 LYN H. sapiens SDL Slorth 0.948625 View
ENSG00000141543 EIF4A3 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948559 View
ENSG00000071564 TCF3 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948557 View
ENSG00000165527 ARF6 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948507 View
ENSG00000101665 SMAD7 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948507 View
ENSG00000075340 ADD2 ENSG00000254087 LYN H. sapiens SDL Slorth 0.948388 View
ENSG00000063660 GPC1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.948388 View
ENSG00000176095 IP6K1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.948322 View
ENSG00000116044 NFE2L2 ENSG00000254087 LYN H. sapiens SSL Slorth 0.948155 View
ENSG00000147010 SH3KBP1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.948106 View
ENSG00000072062 PRKACA ENSG00000254087 LYN H. sapiens SSL Slorth 0.948103 View
ENSG00000204531 POU5F1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.948055 View
ENSG00000114423 CBLB ENSG00000254087 LYN H. sapiens SSL Slorth 0.947996 View
ENSG00000170345 FOS ENSG00000254087 LYN H. sapiens SSL Slorth 0.947959 View
ENSG00000127445 PIN1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.947932 View
ENSG00000137693 YAP1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.947891 View
ENSG00000134982 APC ENSG00000254087 LYN H. sapiens SSL Slorth 0.947844 View
ENSG00000145604 SKP2 ENSG00000254087 LYN H. sapiens SSL Slorth 0.947791 View
ENSG00000126785 RHOJ ENSG00000254087 LYN H. sapiens SDL Slorth 0.947675 View
ENSG00000096968 JAK2 ENSG00000254087 LYN H. sapiens SDL Slorth 0.947626 View
ENSG00000072803 FBXW11 ENSG00000254087 LYN H. sapiens SSL Slorth 0.947579 View
ENSG00000166548 TK2 ENSG00000254087 LYN H. sapiens SDL Slorth 0.947542 View
ENSG00000106346 USP42 ENSG00000254087 LYN H. sapiens SDL Slorth 0.947542 View
ENSG00000101365 IDH3B ENSG00000254087 LYN H. sapiens SDL Slorth 0.947525 View
ENSG00000145506 NKD2 ENSG00000254087 LYN H. sapiens SDL Slorth 0.947461 View