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PTPN11 - LYN
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
PTPN11
ENSG00000179295
JMML
AML
MDS
No drugs in record
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
SH3/SH2 adaptor activity
insulin receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
protein domain specific binding
receptor tyrosine kinase binding
D1 dopamine receptor binding
phospholipase binding
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
cell adhesion molecule binding
peptide hormone receptor binding
PTP1 (S. cerevisiae)
ptp-2 (C. elegans)
csw (D. melanogaster)
LYN
ENSG00000254087
No diseases in record
BOSUTINIB
DASATINIB
PONATINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
receptor binding
platelet-derived growth factor receptor binding
integrin binding
protein binding
ATP binding
SH3 domain binding
ubiquitin protein ligase binding
gamma-tubulin binding
glycosphingolipid binding
ion channel binding
phosphoprotein binding
Src64B (D. melanogaster)