FEN1

ENSG00000168496 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0008309 double-stranded DNA exodeoxyribonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0048256 flap endonuclease activity
GO:0004518 nuclease activity

Drugs

No drugs in record

Diseases

Disease Name
breast cancer

Orthologs

Gene Organism
RAD27 S. cerevisiae
crn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000104365 IKBKB ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.9534 View
ENSG00000134982 APC ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.953351 View
ENSG00000132341 RAN ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.953184 View
ENSG00000078140 UBE2K ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.953109 View
ENSG00000100644 HIF1A ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.953061 View
ENSG00000116016 EPAS1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.953021 View
ENSG00000117748 RPA2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.9529 View
ENSG00000079134 THOC1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.952853 View
ENSG00000168496 FEN1 ENSG00000197122 SRC H. sapiens SDL Slorth 0.952749 View
ENSG00000135446 CDK4 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.952667 View
ENSG00000143799 PARP1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.952467 View
ENSG00000095002 MSH2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.952398 View
ENSG00000047315 POLR2B ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.952214 View
ENSG00000092201 SUPT16H ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.952188 View
ENSG00000061273 HDAC7 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.952082 View
ENSG00000165280 VCP ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.951792 View
ENSG00000123124 WWP1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.951538 View
ENSG00000168496 FEN1 ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.951449 View
ENSG00000145604 SKP2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.951434 View
ENSG00000134057 CCNB1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.951346 View
ENSG00000072518 MARK2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.951299 View
ENSG00000076003 MCM6 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.951141 View
ENSG00000137154 RPS6 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.951101 View
ENSG00000141027 NCOR1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.95105 View
ENSG00000036257 CUL3 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.951028 View
ENSG00000104738 MCM4 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.950873 View
ENSG00000055130 CUL1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.950751 View
ENSG00000063244 U2AF2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.950695 View
ENSG00000144554 FANCD2 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.950474 View
ENSG00000136628 EPRS ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.950467 View
ENSG00000148606 POLR3A ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.950452 View
ENSG00000111276 CDKN1B ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.949814 View
ENSG00000135624 CCT7 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.94971 View
ENSG00000096968 JAK2 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.949692 View
ENSG00000132964 CDK8 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.949548 View
ENSG00000168496 FEN1 ENSG00000204103 MAFB H. sapiens SDL Slorth 0.949462 View
ENSG00000163932 PRKCD ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.949448 View
ENSG00000164109 MAD2L1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.949066 View
ENSG00000168496 FEN1 ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.948975 View
ENSG00000133101 CCNA1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.948663 View