PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000012048 BRCA1 ENSG00000143799 PARP1 H. sapiens SSL BioGRID 2.0 View
ENSG00000139618 BRCA2 ENSG00000143799 PARP1 H. sapiens SSL BioGRID 2.0 View
ENSG00000105486 LIG1 ENSG00000143799 PARP1 H. sapiens SSL BioGRID 1.0 View
ENSG00000143799 PARP1 ENSG00000171848 RRM2 H. sapiens SSL BioGRID 1.0 View
ENSG00000100823 APEX1 ENSG00000143799 PARP1 H. sapiens SSL BioGRID 1.0 View
ENSG00000149554 CHEK1 ENSG00000143799 PARP1 H. sapiens SSL BioGRID 1.0 View
ENSG00000144554 FANCD2 ENSG00000143799 PARP1 H. sapiens SSL BioGRID 1.0 View
ENSG00000168496 FEN1 ENSG00000143799 PARP1 H. sapiens SSL BioGRID 1.0 View
ENSG00000100393 EP300 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.988611 View
ENSG00000012048 BRCA1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.985991 View
ENSG00000132646 PCNA ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.985051 View
ENSG00000133703 KRAS ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.984355 View
ENSG00000067829 IDH3G ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.984215 View
ENSG00000110048 OSBP ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.983897 View
ENSG00000143799 PARP1 ENSG00000221829 FANCG H. sapiens SDL Slorth 0.983876 View
ENSG00000143799 PARP1 ENSG00000160007 ARHGAP35 H. sapiens SDL Slorth 0.983359 View
ENSG00000101365 IDH3B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.983081 View
ENSG00000100372 SLC25A17 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.983078 View
ENSG00000082146 STRADB ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.98304 View
ENSG00000109670 FBXW7 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.982966 View
ENSG00000137073 UBAP2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982946 View
ENSG00000132386 SERPINF1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982847 View
ENSG00000106346 USP42 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982847 View
ENSG00000105204 DYRK1B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982661 View
ENSG00000113240 CLK4 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982619 View
ENSG00000021574 SPAST ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982619 View
ENSG00000077935 SMC1B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.98259 View
ENSG00000116990 MYCL ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982529 View
ENSG00000077380 DYNC1I2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982518 View
ENSG00000079156 OSBPL6 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982518 View
ENSG00000130703 OSBPL2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982518 View
ENSG00000086619 ERO1B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982489 View
ENSG00000102683 SGCG ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982489 View
ENSG00000079337 RAPGEF3 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982345 View
ENSG00000143799 PARP1 ENSG00000165684 SNAPC4 H. sapiens SDL Slorth 0.982323 View
ENSG00000049323 LTBP1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982281 View
ENSG00000100239 PPP6R2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982252 View
ENSG00000102996 MMP15 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982204 View
ENSG00000099785 MARCH2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982184 View
ENSG00000123374 CDK2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.982175 View