PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000137845 ADAM10 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.971469 View
ENSG00000135018 UBQLN1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.971384 View
ENSG00000143799 PARP1 ENSG00000162924 REL H. sapiens SDL Slorth 0.971275 View
ENSG00000064489 BORCS8-MEF2B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.971249 View
ENSG00000064012 CASP8 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.971241 View
ENSG00000143799 PARP1 ENSG00000153561 RMND5A H. sapiens SDL Slorth 0.971185 View
ENSG00000143799 PARP1 ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.971153 View
ENSG00000101146 RAE1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.970949 View
ENSG00000143799 PARP1 ENSG00000170345 FOS H. sapiens SSL Slorth 0.970945 View
ENSG00000143799 PARP1 ENSG00000160789 LMNA H. sapiens SDL Slorth 0.970916 View
ENSG00000143799 PARP1 ENSG00000152284 TCF7L1 H. sapiens SDL Slorth 0.970782 View
ENSG00000143799 PARP1 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.970772 View
ENSG00000143799 PARP1 ENSG00000187522 HSPA14 H. sapiens SDL Slorth 0.970772 View
ENSG00000096717 SIRT1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.970733 View
ENSG00000143799 PARP1 ENSG00000159216 RUNX1 H. sapiens SSL Slorth 0.970728 View
ENSG00000135776 ABCB10 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.970708 View
ENSG00000134982 APC ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.970676 View
ENSG00000004897 CDC27 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.9705 View
ENSG00000143799 PARP1 ENSG00000163098 BIRC8 H. sapiens SDL Slorth 0.970465 View
ENSG00000143799 PARP1 ENSG00000147162 OGT H. sapiens SDL Slorth 0.970463 View
ENSG00000143799 PARP1 ENSG00000145632 PLK2 H. sapiens SDL Slorth 0.970424 View
ENSG00000143799 PARP1 ENSG00000214517 PPME1 H. sapiens SDL Slorth 0.970261 View
ENSG00000143799 PARP1 ENSG00000143970 ASXL2 H. sapiens SDL Slorth 0.970255 View
ENSG00000143799 PARP1 ENSG00000155849 ELMO1 H. sapiens SDL Slorth 0.970173 View
ENSG00000143799 PARP1 ENSG00000149311 ATM H. sapiens SDL Slorth 0.970159 View
ENSG00000143799 PARP1 ENSG00000172115 CYCS H. sapiens SDL Slorth 0.970061 View
ENSG00000134057 CCNB1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.970025 View
ENSG00000005007 UPF1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.969956 View
ENSG00000139631 CSAD ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.969902 View
ENSG00000011454 RABGAP1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.969892 View
ENSG00000139687 RB1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.969878 View
ENSG00000143799 PARP1 ENSG00000166851 PLK1 H. sapiens SDL Slorth 0.969869 View
ENSG00000143799 PARP1 ENSG00000204389 HSPA1A H. sapiens SDL Slorth 0.969818 View
ENSG00000143799 PARP1 ENSG00000145604 SKP2 H. sapiens SDL Slorth 0.969678 View
ENSG00000143799 PARP1 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.969653 View
ENSG00000036257 CUL3 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.969578 View
ENSG00000122966 CIT ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.969552 View
ENSG00000124232 RBPJL ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.969411 View
ENSG00000143799 PARP1 ENSG00000181449 SOX2 H. sapiens SDL Slorth 0.969334 View
ENSG00000143799 PARP1 ENSG00000175592 FOSL1 H. sapiens SDL Slorth 0.969285 View