CASP8 - PARP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
PARP1	ENSG00000143799	No diseases in record	OLAPARIB	DNA binding DNA ligase (ATP) activity NAD+ ADP-ribosyltransferase activity protein binding transcription factor binding zinc ion binding enzyme binding protein kinase binding estrogen receptor binding identical protein binding histone deacetylase binding protein N-terminus binding NAD binding R-SMAD binding	Parp (D. melanogaster)