CASP8

ENSG00000064012 - H. sapiens

Pathways

Go term Description
GO:0004197 cysteine-type endopeptidase activity
GO:0005123 death receptor binding
GO:0005164 tumor necrosis factor receptor binding
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0031625 ubiquitin protein ligase binding
GO:0032403 protein complex binding
GO:0035877 death effector domain binding
GO:0042802 identical protein binding
GO:0097110 scaffold protein binding
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Drugs

No drugs in record

Diseases

Disease Name
hepatocellular
oral squamous cell
breast

Orthologs

Gene Organism
Dredd D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000064012 CASP8 ENSG00000134086 VHL H. sapiens SSL BioGRID 1.0 View
ENSG00000064012 CASP8 ENSG00000136807 CDK9 H. sapiens SSL BioGRID 1.0 View
ENSG00000064012 CASP8 ENSG00000111276 CDKN1B H. sapiens SSL BioGRID 1.0 View
ENSG00000064012 CASP8 ENSG00000149554 CHEK1 H. sapiens SSL BioGRID 1.0 View
ENSG00000064012 CASP8 ENSG00000198793 MTOR H. sapiens SSL BioGRID 1.0 View
ENSG00000064012 CASP8 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.987706 View
ENSG00000064012 CASP8 ENSG00000137843 PAK6 H. sapiens SDL Slorth 0.984766 View
ENSG00000064012 CASP8 ENSG00000169372 CRADD H. sapiens SDL Slorth 0.983433 View
ENSG00000021574 SPAST ENSG00000064012 CASP8 H. sapiens SDL Slorth 0.982809 View
ENSG00000005339 CREBBP ENSG00000064012 CASP8 H. sapiens SDL Slorth 0.982295 View
ENSG00000064012 CASP8 ENSG00000162889 MAPKAPK2 H. sapiens SDL Slorth 0.981824 View
ENSG00000064012 CASP8 ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.981486 View
ENSG00000064012 CASP8 ENSG00000102010 BMX H. sapiens SDL Slorth 0.980926 View
ENSG00000064012 CASP8 ENSG00000110330 BIRC2 H. sapiens SDL Slorth 0.980897 View
ENSG00000064012 CASP8 ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.980541 View
ENSG00000064012 CASP8 ENSG00000100968 NFATC4 H. sapiens SDL Slorth 0.980407 View
ENSG00000064012 CASP8 ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.980301 View
ENSG00000064012 CASP8 ENSG00000100092 SH3BP1 H. sapiens SDL Slorth 0.980281 View
ENSG00000064012 CASP8 ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.979942 View
ENSG00000064012 CASP8 ENSG00000112144 ICK H. sapiens SDL Slorth 0.979847 View
ENSG00000064012 CASP8 ENSG00000157601 MX1 H. sapiens SDL Slorth 0.979644 View
ENSG00000064012 CASP8 ENSG00000107929 LARP4B H. sapiens SDL Slorth 0.979309 View
ENSG00000064012 CASP8 ENSG00000101349 PAK5 H. sapiens SDL Slorth 0.979098 View
ENSG00000064012 CASP8 ENSG00000100393 EP300 H. sapiens SDL Slorth 0.978762 View
ENSG00000064012 CASP8 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.978645 View
ENSG00000064012 CASP8 ENSG00000073614 KDM5A H. sapiens SDL Slorth 0.978615 View
ENSG00000064012 CASP8 ENSG00000100320 RBFOX2 H. sapiens SDL Slorth 0.978463 View
ENSG00000064012 CASP8 ENSG00000115221 ITGB6 H. sapiens SDL Slorth 0.978414 View
ENSG00000064012 CASP8 ENSG00000107036 RIC1 H. sapiens SDL Slorth 0.978279 View
ENSG00000064012 CASP8 ENSG00000135090 TAOK3 H. sapiens SDL Slorth 0.978183 View
ENSG00000064012 CASP8 ENSG00000143420 ENSA H. sapiens SDL Slorth 0.978099 View
ENSG00000004848 ARX ENSG00000064012 CASP8 H. sapiens SDL Slorth 0.977843 View
ENSG00000064012 CASP8 ENSG00000132005 RFX1 H. sapiens SDL Slorth 0.977643 View
ENSG00000064012 CASP8 ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.977415 View
ENSG00000041353 RAB27B ENSG00000064012 CASP8 H. sapiens SDL Slorth 0.977368 View
ENSG00000064012 CASP8 ENSG00000128512 DOCK4 H. sapiens SDL Slorth 0.977267 View
ENSG00000064012 CASP8 ENSG00000124784 RIOK1 H. sapiens SDL Slorth 0.977246 View
ENSG00000064012 CASP8 ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.977157 View
ENSG00000064012 CASP8 ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.977017 View
ENSG00000064012 CASP8 ENSG00000081059 TCF7 H. sapiens SDL Slorth 0.977017 View