CASP8

ENSG00000064012 - H. sapiens

Pathways

Go term Description
GO:0004197 cysteine-type endopeptidase activity
GO:0005123 death receptor binding
GO:0005164 tumor necrosis factor receptor binding
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0031625 ubiquitin protein ligase binding
GO:0032403 protein complex binding
GO:0035877 death effector domain binding
GO:0042802 identical protein binding
GO:0097110 scaffold protein binding
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Drugs

No drugs in record

Diseases

Disease Name
hepatocellular
oral squamous cell
breast

Orthologs

Gene Organism
Dredd D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000064012 CASP8 ENSG00000096968 JAK2 H. sapiens SSL Slorth 0.95786 View
ENSG00000064012 CASP8 ENSG00000170312 CDK1 H. sapiens SSL Slorth 0.957802 View
ENSG00000064012 CASP8 ENSG00000104852 SNRNP70 H. sapiens SSL Slorth 0.957782 View
ENSG00000064012 CASP8 ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.957747 View
ENSG00000064012 CASP8 ENSG00000141543 EIF4A3 H. sapiens SSL Slorth 0.957741 View
ENSG00000064012 CASP8 ENSG00000114166 KAT2B H. sapiens SSL Slorth 0.957725 View
ENSG00000064012 CASP8 ENSG00000105229 PIAS4 H. sapiens SSL Slorth 0.957715 View
ENSG00000064012 CASP8 ENSG00000118689 FOXO3 H. sapiens SSL Slorth 0.957683 View
ENSG00000064012 CASP8 ENSG00000165025 SYK H. sapiens SSL Slorth 0.957642 View
ENSG00000064012 CASP8 ENSG00000145632 PLK2 H. sapiens SDL Slorth 0.957546 View
ENSG00000064012 CASP8 ENSG00000171791 BCL2 H. sapiens SSL Slorth 0.957508 View
ENSG00000064012 CASP8 ENSG00000136237 RAPGEF5 H. sapiens SDL Slorth 0.95734 View
ENSG00000064012 CASP8 ENSG00000169756 LIMS1 H. sapiens SDL Slorth 0.957276 View
ENSG00000064012 CASP8 ENSG00000165506 DNAAF2 H. sapiens SDL Slorth 0.957257 View
ENSG00000064012 CASP8 ENSG00000187522 HSPA14 H. sapiens SDL Slorth 0.957257 View
ENSG00000064012 CASP8 ENSG00000128607 KLHDC10 H. sapiens SDL Slorth 0.95721 View
ENSG00000064012 CASP8 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.957135 View
ENSG00000064012 CASP8 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.957048 View
ENSG00000064012 CASP8 ENSG00000129152 MYOD1 H. sapiens SSL Slorth 0.957045 View
ENSG00000064012 CASP8 ENSG00000113758 DBN1 H. sapiens SDL Slorth 0.957022 View
ENSG00000064012 CASP8 ENSG00000111424 VDR H. sapiens SSL Slorth 0.956957 View
ENSG00000064012 CASP8 ENSG00000166501 PRKCB H. sapiens SDL Slorth 0.956954 View
ENSG00000064012 CASP8 ENSG00000123405 NFE2 H. sapiens SDL Slorth 0.956901 View
ENSG00000064012 CASP8 ENSG00000103275 UBE2I H. sapiens SSL Slorth 0.95686 View
ENSG00000064012 CASP8 ENSG00000091409 ITGA6 H. sapiens SDL Slorth 0.956859 View
ENSG00000064012 CASP8 ENSG00000104365 IKBKB H. sapiens SSL Slorth 0.956843 View
ENSG00000064012 CASP8 ENSG00000103479 RBL2 H. sapiens SSL Slorth 0.956738 View
ENSG00000064012 CASP8 ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.956722 View
ENSG00000064012 CASP8 ENSG00000100505 TRIM9 H. sapiens SDL Slorth 0.956473 View
ENSG00000064012 CASP8 ENSG00000177889 UBE2N H. sapiens SDL Slorth 0.956468 View
ENSG00000064012 CASP8 ENSG00000137486 ARRB1 H. sapiens SSL Slorth 0.956423 View
ENSG00000064012 CASP8 ENSG00000082701 GSK3B H. sapiens SSL Slorth 0.956342 View
ENSG00000064012 CASP8 ENSG00000134070 IRAK2 H. sapiens SDL Slorth 0.956251 View
ENSG00000064012 CASP8 ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.956086 View
ENSG00000005007 UPF1 ENSG00000064012 CASP8 H. sapiens SSL Slorth 0.956011 View
ENSG00000064012 CASP8 ENSG00000143867 OSR1 H. sapiens SDL Slorth 0.955951 View
ENSG00000064012 CASP8 ENSG00000112592 TBP H. sapiens SSL Slorth 0.955879 View
ENSG00000064012 CASP8 ENSG00000185591 SP1 H. sapiens SSL Slorth 0.955858 View
ENSG00000064012 CASP8 ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.955824 View
ENSG00000064012 CASP8 ENSG00000158987 RAPGEF6 H. sapiens SDL Slorth 0.955805 View