UPF1 - CASP8

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UPF1	ENSG00000005007	No diseases in record	No drugs in record	chromatin binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding zinc ion binding telomeric DNA binding DNA binding	NAM7 (S. cerevisiae) smg-2 (C. elegans) Upf1 (D. melanogaster)
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)