CASP8

ENSG00000064012 - H. sapiens

Pathways

Go term Description
GO:0004197 cysteine-type endopeptidase activity
GO:0005123 death receptor binding
GO:0005164 tumor necrosis factor receptor binding
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0031625 ubiquitin protein ligase binding
GO:0032403 protein complex binding
GO:0035877 death effector domain binding
GO:0042802 identical protein binding
GO:0097110 scaffold protein binding
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Drugs

No drugs in record

Diseases

Disease Name
hepatocellular
oral squamous cell
breast

Orthologs

Gene Organism
Dredd D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000064012 CASP8 ENSG00000116560 SFPQ H. sapiens SSL Slorth 0.960289 View
ENSG00000064012 CASP8 ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.960078 View
ENSG00000064012 CASP8 ENSG00000106462 EZH2 H. sapiens SSL Slorth 0.960076 View
ENSG00000061273 HDAC7 ENSG00000064012 CASP8 H. sapiens SSL Slorth 0.959933 View
ENSG00000064012 CASP8 ENSG00000154237 LRRK1 H. sapiens SDL Slorth 0.959888 View
ENSG00000064012 CASP8 ENSG00000103197 TSC2 H. sapiens SSL Slorth 0.959809 View
ENSG00000064012 CASP8 ENSG00000131196 NFATC1 H. sapiens SDL Slorth 0.959796 View
ENSG00000055130 CUL1 ENSG00000064012 CASP8 H. sapiens SSL Slorth 0.959779 View
ENSG00000064012 CASP8 ENSG00000110422 HIPK3 H. sapiens SDL Slorth 0.95974 View
ENSG00000064012 CASP8 ENSG00000135144 DTX1 H. sapiens SDL Slorth 0.959717 View
ENSG00000064012 CASP8 ENSG00000140464 PML H. sapiens SSL Slorth 0.959711 View
ENSG00000064012 CASP8 ENSG00000187555 USP7 H. sapiens SSL Slorth 0.959539 View
ENSG00000064012 CASP8 ENSG00000080824 HSP90AA1 H. sapiens SDL Slorth 0.959347 View
ENSG00000064012 CASP8 ENSG00000131508 UBE2D2 H. sapiens SSL Slorth 0.959227 View
ENSG00000064012 CASP8 ENSG00000137764 MAP2K5 H. sapiens SDL Slorth 0.959227 View
ENSG00000064012 CASP8 ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.959222 View
ENSG00000001626 CFTR ENSG00000064012 CASP8 H. sapiens SSL Slorth 0.959026 View
ENSG00000064012 CASP8 ENSG00000166483 WEE1 H. sapiens SSL Slorth 0.958996 View
ENSG00000010671 BTK ENSG00000064012 CASP8 H. sapiens SDL Slorth 0.958962 View
ENSG00000064012 CASP8 ENSG00000088832 FKBP1A H. sapiens SSL Slorth 0.958958 View
ENSG00000064012 CASP8 ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.958922 View
ENSG00000064012 CASP8 ENSG00000168148 HIST3H3 H. sapiens SSL Slorth 0.958708 View
ENSG00000064012 CASP8 ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.958701 View
ENSG00000064012 CASP8 ENSG00000184675 AMER1 H. sapiens SDL Slorth 0.958684 View
ENSG00000064012 CASP8 ENSG00000101966 XIAP H. sapiens SSL Slorth 0.958634 View
ENSG00000064012 CASP8 ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.958538 View
ENSG00000064012 CASP8 ENSG00000134308 YWHAQ H. sapiens SSL Slorth 0.958495 View
ENSG00000064012 CASP8 ENSG00000138376 BARD1 H. sapiens SSL Slorth 0.958488 View
ENSG00000064012 CASP8 ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.958264 View
ENSG00000064012 CASP8 ENSG00000101197 BIRC7 H. sapiens SDL Slorth 0.958262 View
ENSG00000064012 CASP8 ENSG00000100359 SGSM3 H. sapiens SDL Slorth 0.958242 View
ENSG00000064012 CASP8 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.958235 View
ENSG00000064012 CASP8 ENSG00000173039 RELA H. sapiens SSL Slorth 0.958233 View
ENSG00000064012 CASP8 ENSG00000110107 PRPF19 H. sapiens SSL Slorth 0.958139 View
ENSG00000064012 CASP8 ENSG00000171621 SPSB1 H. sapiens SDL Slorth 0.958107 View
ENSG00000064012 CASP8 ENSG00000175093 SPSB4 H. sapiens SDL Slorth 0.958107 View
ENSG00000064012 CASP8 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.958016 View
ENSG00000064012 CASP8 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.958014 View
ENSG00000012048 BRCA1 ENSG00000064012 CASP8 H. sapiens SDL Slorth 0.957984 View
ENSG00000064012 CASP8 ENSG00000149930 TAOK2 H. sapiens SDL Slorth 0.957888 View