BTK

ENSG00000010671 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
IBRUTINIB Tyrosine-protein kinase BTK inhibitor

Diseases

Disease Name
CLL
mantle cell lymphoma
WM

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000010671 BTK ENSG00000136997 MYC H. sapiens SDL BioGRID 1.0 View
ENSG00000010671 BTK ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.983438 View
ENSG00000010671 BTK ENSG00000110395 CBL H. sapiens SDL Slorth 0.982986 View
ENSG00000010671 BTK ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.981824 View
ENSG00000010671 BTK ENSG00000164924 YWHAZ H. sapiens SDL Slorth 0.981801 View
ENSG00000010671 BTK ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.981475 View
ENSG00000010671 BTK ENSG00000170312 CDK1 H. sapiens SDL Slorth 0.981435 View
ENSG00000010671 BTK ENSG00000141027 NCOR1 H. sapiens SDL Slorth 0.98075 View
ENSG00000010671 BTK ENSG00000067560 RHOA H. sapiens SDL Slorth 0.980372 View
ENSG00000010671 BTK ENSG00000166913 YWHAB H. sapiens SDL Slorth 0.979325 View
ENSG00000010671 BTK ENSG00000170606 HSPA4 H. sapiens SDL Slorth 0.979311 View
ENSG00000010671 BTK ENSG00000186868 MAPT H. sapiens SDL Slorth 0.979212 View
ENSG00000010671 BTK ENSG00000158092 NCK1 H. sapiens SDL Slorth 0.979087 View
ENSG00000010671 BTK ENSG00000112592 TBP H. sapiens SDL Slorth 0.978708 View
ENSG00000010671 BTK ENSG00000096384 HSP90AB1 H. sapiens SDL Slorth 0.978585 View
ENSG00000010671 BTK ENSG00000070831 CDC42 H. sapiens SDL Slorth 0.97837 View
ENSG00000010671 BTK ENSG00000132383 RPA1 H. sapiens SDL Slorth 0.977716 View
ENSG00000010671 BTK ENSG00000124181 PLCG1 H. sapiens SDL Slorth 0.977583 View
ENSG00000010671 BTK ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.977582 View
ENSG00000010671 BTK ENSG00000047315 POLR2B H. sapiens SDL Slorth 0.977368 View
ENSG00000010671 BTK ENSG00000036257 CUL3 H. sapiens SDL Slorth 0.977246 View
ENSG00000010671 BTK ENSG00000137693 YAP1 H. sapiens SDL Slorth 0.977031 View
ENSG00000010671 BTK ENSG00000105568 PPP2R1A H. sapiens SDL Slorth 0.976933 View
ENSG00000010671 BTK ENSG00000100393 EP300 H. sapiens SDL Slorth 0.976882 View
ENSG00000010671 BTK ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.976482 View
ENSG00000010671 BTK ENSG00000112062 MAPK14 H. sapiens SDL Slorth 0.976094 View
ENSG00000010671 BTK ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.976021 View
ENSG00000010671 BTK ENSG00000103275 UBE2I H. sapiens SDL Slorth 0.975973 View
ENSG00000010671 BTK ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.97595 View
ENSG00000010671 BTK ENSG00000141510 TP53 H. sapiens SDL Slorth 0.975853 View
ENSG00000010671 BTK ENSG00000163960 UBXN7 H. sapiens SDL Slorth 0.975789 View
ENSG00000010671 BTK ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.97578 View
ENSG00000010671 BTK ENSG00000121022 COPS5 H. sapiens SDL Slorth 0.975726 View
ENSG00000010671 BTK ENSG00000165280 VCP H. sapiens SDL Slorth 0.975706 View
ENSG00000010671 BTK ENSG00000100644 HIF1A H. sapiens SDL Slorth 0.975706 View
ENSG00000010671 BTK ENSG00000197299 BLM H. sapiens SDL Slorth 0.975539 View
ENSG00000010671 BTK ENSG00000142192 APP H. sapiens SDL Slorth 0.97552 View
ENSG00000010671 BTK ENSG00000099817 POLR2E H. sapiens SDL Slorth 0.975464 View
ENSG00000010671 BTK ENSG00000080824 HSP90AA1 H. sapiens SDL Slorth 0.975369 View
ENSG00000010671 BTK ENSG00000182866 LCK H. sapiens SDL Slorth 0.975298 View