BTK

ENSG00000010671 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
IBRUTINIB Tyrosine-protein kinase BTK inhibitor

Diseases

Disease Name
CLL
mantle cell lymphoma
WM

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000010671 BTK ENSG00000039068 CDH1 H. sapiens SDL Slorth 0.918763 View
ENSG00000010671 BTK ENSG00000142864 SERBP1 H. sapiens SDL Slorth 0.918749 View
ENSG00000010671 BTK ENSG00000127445 PIN1 H. sapiens SDL Slorth 0.918432 View
ENSG00000010671 BTK ENSG00000168438 CDC40 H. sapiens SDL Slorth 0.917279 View
ENSG00000010671 BTK ENSG00000132170 PPARG H. sapiens SDL Slorth 0.916139 View
ENSG00000010671 BTK ENSG00000108094 CUL2 H. sapiens SDL Slorth 0.915553 View
ENSG00000010671 BTK ENSG00000197442 MAP3K5 H. sapiens SDL Slorth 0.91437 View
ENSG00000010671 BTK ENSG00000077097 TOP2B H. sapiens SDL Slorth 0.913713 View
ENSG00000010671 BTK ENSG00000072110 ACTN1 H. sapiens SDL Slorth 0.913662 View
ENSG00000010671 BTK ENSG00000165731 RET H. sapiens SDL Slorth 0.913484 View
ENSG00000010671 BTK ENSG00000139842 CUL4A H. sapiens SDL Slorth 0.912603 View
ENSG00000010671 BTK ENSG00000077312 SNRPA H. sapiens SDL Slorth 0.90919 View
ENSG00000010671 BTK ENSG00000085733 CTTN H. sapiens SDL Slorth 0.9083 View
ENSG00000010671 BTK ENSG00000184634 MED12 H. sapiens SDL Slorth 0.907885 View
ENSG00000010671 BTK ENSG00000111424 VDR H. sapiens SDL Slorth 0.907828 View
ENSG00000010671 BTK ENSG00000103197 TSC2 H. sapiens SDL Slorth 0.907323 View
ENSG00000010671 BTK ENSG00000106211 HSPB1 H. sapiens SDL Slorth 0.9064 View
ENSG00000010671 BTK ENSG00000119318 RAD23B H. sapiens SDL Slorth 0.904634 View
ENSG00000010671 BTK ENSG00000136930 PSMB7 H. sapiens SDL Slorth 0.902834 View
ENSG00000010671 BTK ENSG00000159377 PSMB4 H. sapiens SDL Slorth 0.902641 View
ENSG00000010671 BTK ENSG00000106588 PSMA2 H. sapiens SDL Slorth 0.902622 View
ENSG00000010671 BTK ENSG00000129084 PSMA1 H. sapiens SDL Slorth 0.902622 View
ENSG00000010671 BTK ENSG00000023445 BIRC3 H. sapiens SDL Slorth 0.902003 View
ENSG00000010671 BTK ENSG00000198793 MTOR H. sapiens SDL Slorth 0.901443 View
ENSG00000010671 BTK ENSG00000134982 APC H. sapiens SDL Slorth 0.900645 View
ENSG00000010671 BTK ENSG00000159216 RUNX1 H. sapiens SDL Slorth 0.900536 View
ENSG00000010671 BTK ENSG00000164885 CDK5 H. sapiens SDL Slorth 0.900049 View
ENSG00000010671 BTK ENSG00000176105 YES1 H. sapiens SSL Slorth 0.864905 View
ENSG00000010671 BTK ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.855389 View
ENSG00000010671 BTK ENSG00000204843 DCTN1 H. sapiens SSL Slorth 0.819034 View
ENSG00000010671 BTK ENSG00000109670 FBXW7 H. sapiens SSL Slorth 0.801707 View
ENSG00000006451 RALA ENSG00000010671 BTK H. sapiens SSL Slorth 0.794659 View
ENSG00000010671 BTK ENSG00000116473 RAP1A H. sapiens SSL Slorth 0.787265 View