BTK

ENSG00000010671 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
IBRUTINIB Tyrosine-protein kinase BTK inhibitor

Diseases

Disease Name
CLL
mantle cell lymphoma
WM

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000010671 BTK ENSG00000096968 JAK2 H. sapiens SDL Slorth 0.974971 View
ENSG00000010671 BTK ENSG00000100030 MAPK1 H. sapiens SDL Slorth 0.974808 View
ENSG00000010671 BTK ENSG00000197122 SRC H. sapiens SDL Slorth 0.974467 View
ENSG00000010671 BTK ENSG00000082898 XPO1 H. sapiens SDL Slorth 0.974445 View
ENSG00000010671 BTK ENSG00000154229 PRKCA H. sapiens SDL Slorth 0.974401 View
ENSG00000010671 BTK ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.974333 View
ENSG00000010671 BTK ENSG00000114166 KAT2B H. sapiens SDL Slorth 0.974244 View
ENSG00000010671 BTK ENSG00000132646 PCNA H. sapiens SDL Slorth 0.974126 View
ENSG00000010671 BTK ENSG00000167986 DDB1 H. sapiens SDL Slorth 0.974118 View
ENSG00000010671 BTK ENSG00000185591 SP1 H. sapiens SDL Slorth 0.974072 View
ENSG00000010671 BTK ENSG00000253729 PRKDC H. sapiens SDL Slorth 0.973971 View
ENSG00000010671 BTK ENSG00000084774 CAD H. sapiens SDL Slorth 0.973936 View
ENSG00000010671 BTK ENSG00000169083 AR H. sapiens SDL Slorth 0.973856 View
ENSG00000010671 BTK ENSG00000175104 TRAF6 H. sapiens SDL Slorth 0.973814 View
ENSG00000010671 BTK ENSG00000175054 ATR H. sapiens SDL Slorth 0.973109 View
ENSG00000010671 BTK ENSG00000109971 HSPA8 H. sapiens SDL Slorth 0.972994 View
ENSG00000010671 BTK ENSG00000102882 MAPK3 H. sapiens SDL Slorth 0.972789 View
ENSG00000010671 BTK ENSG00000198668 CALM1 H. sapiens SDL Slorth 0.972481 View
ENSG00000010671 BTK ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.972401 View
ENSG00000010671 BTK ENSG00000169398 PTK2 H. sapiens SDL Slorth 0.972241 View
ENSG00000010671 BTK ENSG00000124762 CDKN1A H. sapiens SDL Slorth 0.972186 View
ENSG00000010671 BTK ENSG00000174231 PRPF8 H. sapiens SDL Slorth 0.972103 View
ENSG00000010671 BTK ENSG00000122406 RPL5 H. sapiens SDL Slorth 0.971901 View
ENSG00000010671 BTK ENSG00000100387 RBX1 H. sapiens SDL Slorth 0.971821 View
ENSG00000010671 BTK ENSG00000164305 CASP3 H. sapiens SDL Slorth 0.971779 View
ENSG00000010671 BTK ENSG00000115524 SF3B1 H. sapiens SDL Slorth 0.970975 View
ENSG00000010671 BTK ENSG00000150093 ITGB1 H. sapiens SDL Slorth 0.970973 View
ENSG00000010671 BTK ENSG00000111276 CDKN1B H. sapiens SDL Slorth 0.970895 View
ENSG00000010671 BTK ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.970842 View
ENSG00000010671 BTK ENSG00000101361 NOP56 H. sapiens SDL Slorth 0.970807 View
ENSG00000010671 BTK ENSG00000069869 NEDD4 H. sapiens SDL Slorth 0.970749 View
ENSG00000010671 BTK ENSG00000100028 SNRPD3 H. sapiens SDL Slorth 0.970156 View
ENSG00000010671 BTK ENSG00000113558 SKP1 H. sapiens SDL Slorth 0.970117 View
ENSG00000010671 BTK ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.969864 View
ENSG00000010671 BTK ENSG00000112306 RPS12 H. sapiens SDL Slorth 0.969806 View
ENSG00000010671 BTK ENSG00000055130 CUL1 H. sapiens SDL Slorth 0.969744 View
ENSG00000010671 BTK ENSG00000150991 UBC H. sapiens SDL Slorth 0.969727 View
ENSG00000010671 BTK ENSG00000145604 SKP2 H. sapiens SDL Slorth 0.969705 View
ENSG00000010671 BTK ENSG00000166167 BTRC H. sapiens SDL Slorth 0.96966 View
ENSG00000010671 BTK ENSG00000136238 RAC1 H. sapiens SDL Slorth 0.969375 View