BTK

ENSG00000010671 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
IBRUTINIB Tyrosine-protein kinase BTK inhibitor

Diseases

Disease Name
CLL
mantle cell lymphoma
WM

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000010671 BTK ENSG00000089159 PXN H. sapiens SDL Slorth 0.943462 View
ENSG00000010671 BTK ENSG00000127022 CANX H. sapiens SDL Slorth 0.943423 View
ENSG00000010671 BTK ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.942792 View
ENSG00000010671 BTK ENSG00000103035 PSMD7 H. sapiens SDL Slorth 0.942691 View
ENSG00000010671 BTK ENSG00000196396 PTPN1 H. sapiens SDL Slorth 0.942 View
ENSG00000010671 BTK ENSG00000104375 STK3 H. sapiens SDL Slorth 0.941006 View
ENSG00000010671 BTK ENSG00000188906 LRRK2 H. sapiens SDL Slorth 0.940403 View
ENSG00000010671 BTK ENSG00000107643 MAPK8 H. sapiens SDL Slorth 0.940242 View
ENSG00000010671 BTK ENSG00000149554 CHEK1 H. sapiens SDL Slorth 0.940227 View
ENSG00000010671 BTK ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.940155 View
ENSG00000010671 BTK ENSG00000141480 ARRB2 H. sapiens SDL Slorth 0.939975 View
ENSG00000010671 BTK ENSG00000128052 KDR H. sapiens SDL Slorth 0.939469 View
ENSG00000010671 BTK ENSG00000135018 UBQLN1 H. sapiens SDL Slorth 0.939227 View
ENSG00000010671 BTK ENSG00000117399 CDC20 H. sapiens SDL Slorth 0.938656 View
ENSG00000010671 BTK ENSG00000198742 SMURF1 H. sapiens SDL Slorth 0.938501 View
ENSG00000010671 BTK ENSG00000087586 AURKA H. sapiens SDL Slorth 0.938203 View
ENSG00000010671 BTK ENSG00000166851 PLK1 H. sapiens SDL Slorth 0.937991 View
ENSG00000010671 BTK ENSG00000141736 ERBB2 H. sapiens SDL Slorth 0.937745 View
ENSG00000010671 BTK ENSG00000254087 LYN H. sapiens SDL Slorth 0.937011 View
ENSG00000010671 BTK ENSG00000110092 CCND1 H. sapiens SDL Slorth 0.936481 View
ENSG00000010671 BTK ENSG00000079999 KEAP1 H. sapiens SDL Slorth 0.93536 View
ENSG00000010671 BTK ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.933347 View
ENSG00000010671 BTK ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.932496 View
ENSG00000010671 BTK ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.93235 View
ENSG00000010671 BTK ENSG00000108953 YWHAE H. sapiens SDL Slorth 0.931781 View
ENSG00000010671 BTK ENSG00000063244 U2AF2 H. sapiens SDL Slorth 0.931772 View
ENSG00000010671 BTK ENSG00000101343 CRNKL1 H. sapiens SDL Slorth 0.930932 View
ENSG00000010671 BTK ENSG00000145386 CCNA2 H. sapiens SDL Slorth 0.929896 View
ENSG00000010671 BTK ENSG00000084676 NCOA1 H. sapiens SDL Slorth 0.929744 View
ENSG00000010671 BTK ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929503 View
ENSG00000010671 BTK ENSG00000168090 COPS6 H. sapiens SDL Slorth 0.929127 View
ENSG00000010671 BTK ENSG00000130726 TRIM28 H. sapiens SDL Slorth 0.926756 View
ENSG00000010671 BTK ENSG00000107581 EIF3A H. sapiens SDL Slorth 0.926128 View
ENSG00000010671 BTK ENSG00000101665 SMAD7 H. sapiens SDL Slorth 0.923911 View
ENSG00000010671 BTK ENSG00000185359 HGS H. sapiens SDL Slorth 0.923771 View
ENSG00000010671 BTK ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.923023 View
ENSG00000010671 BTK ENSG00000244687 UBE2V1 H. sapiens SDL Slorth 0.922672 View
ENSG00000010671 BTK ENSG00000114062 UBE3A H. sapiens SDL Slorth 0.922648 View
ENSG00000010671 BTK ENSG00000196235 SUPT5H H. sapiens SDL Slorth 0.921362 View
ENSG00000010671 BTK ENSG00000165392 WRN H. sapiens SDL Slorth 0.918983 View