BTK

ENSG00000010671 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
IBRUTINIB Tyrosine-protein kinase BTK inhibitor

Diseases

Disease Name
CLL
mantle cell lymphoma
WM

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000010671 BTK ENSG00000108424 KPNB1 H. sapiens SDL Slorth 0.969237 View
ENSG00000010671 BTK ENSG00000171791 BCL2 H. sapiens SDL Slorth 0.969191 View
ENSG00000010671 BTK ENSG00000183431 SF3A3 H. sapiens SDL Slorth 0.968781 View
ENSG00000010671 BTK ENSG00000183684 ALYREF H. sapiens SDL Slorth 0.968448 View
ENSG00000010671 BTK ENSG00000139687 RB1 H. sapiens SDL Slorth 0.96833 View
ENSG00000010671 BTK ENSG00000101966 XIAP H. sapiens SDL Slorth 0.968161 View
ENSG00000010671 BTK ENSG00000147133 TAF1 H. sapiens SDL Slorth 0.96814 View
ENSG00000010671 BTK ENSG00000012048 BRCA1 H. sapiens SDL Slorth 0.967958 View
ENSG00000010671 BTK ENSG00000131876 SNRPA1 H. sapiens SDL Slorth 0.96788 View
ENSG00000010671 BTK ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.967879 View
ENSG00000010671 BTK ENSG00000113575 PPP2CA H. sapiens SDL Slorth 0.967799 View
ENSG00000010671 BTK ENSG00000110107 PRPF19 H. sapiens SDL Slorth 0.967731 View
ENSG00000010671 BTK ENSG00000169375 SIN3A H. sapiens SDL Slorth 0.967426 View
ENSG00000010671 BTK ENSG00000121774 KHDRBS1 H. sapiens SDL Slorth 0.967293 View
ENSG00000010671 BTK ENSG00000020922 MRE11 H. sapiens SDL Slorth 0.967238 View
ENSG00000010671 BTK ENSG00000175792 RUVBL1 H. sapiens SDL Slorth 0.967225 View
ENSG00000010671 BTK ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.966807 View
ENSG00000010671 BTK ENSG00000129559 NEDD8 H. sapiens SDL Slorth 0.966509 View
ENSG00000010671 BTK ENSG00000163930 BAP1 H. sapiens SDL Slorth 0.966441 View
ENSG00000010671 BTK ENSG00000140988 RPS2 H. sapiens SDL Slorth 0.966306 View
ENSG00000010671 BTK ENSG00000089157 RPLP0 H. sapiens SDL Slorth 0.966299 View
ENSG00000010671 BTK ENSG00000156482 RPL30 H. sapiens SDL Slorth 0.966299 View
ENSG00000010671 BTK ENSG00000116251 RPL22 H. sapiens SDL Slorth 0.966185 View
ENSG00000010671 BTK ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.965867 View
ENSG00000010671 BTK ENSG00000124486 USP9X H. sapiens SDL Slorth 0.9656 View
ENSG00000010671 BTK ENSG00000147604 RPL7 H. sapiens SDL Slorth 0.965582 View
ENSG00000010671 BTK ENSG00000137154 RPS6 H. sapiens SDL Slorth 0.965424 View
ENSG00000010671 BTK ENSG00000082701 GSK3B H. sapiens SDL Slorth 0.965202 View
ENSG00000010671 BTK ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.96497 View
ENSG00000010671 BTK ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.964289 View
ENSG00000010671 BTK ENSG00000177600 RPLP2 H. sapiens SDL Slorth 0.964223 View
ENSG00000010671 BTK ENSG00000101266 CSNK2A1 H. sapiens SDL Slorth 0.964015 View
ENSG00000010671 BTK ENSG00000183207 RUVBL2 H. sapiens SDL Slorth 0.963919 View
ENSG00000010671 BTK ENSG00000140464 PML H. sapiens SDL Slorth 0.963882 View
ENSG00000010671 BTK ENSG00000167658 EEF2 H. sapiens SDL Slorth 0.963862 View
ENSG00000010671 BTK ENSG00000173039 RELA H. sapiens SDL Slorth 0.963691 View
ENSG00000010671 BTK ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.963651 View
ENSG00000010671 BTK ENSG00000168028 RPSA H. sapiens SDL Slorth 0.963596 View
ENSG00000010671 BTK ENSG00000071082 RPL31 H. sapiens SDL Slorth 0.963586 View
ENSG00000010671 BTK ENSG00000105640 RPL18A H. sapiens SDL Slorth 0.963579 View