BTK

ENSG00000010671 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
IBRUTINIB Tyrosine-protein kinase BTK inhibitor

Diseases

Disease Name
CLL
mantle cell lymphoma
WM

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000010671 BTK ENSG00000134086 VHL H. sapiens SDL Slorth 0.955053 View
ENSG00000010671 BTK ENSG00000010810 FYN H. sapiens SDL Slorth 0.954816 View
ENSG00000010671 BTK ENSG00000141367 CLTC H. sapiens SDL Slorth 0.954163 View
ENSG00000010671 BTK ENSG00000051180 RAD51 H. sapiens SDL Slorth 0.954098 View
ENSG00000010671 BTK ENSG00000171720 HDAC3 H. sapiens SDL Slorth 0.953876 View
ENSG00000010671 BTK ENSG00000213741 RPS29 H. sapiens SDL Slorth 0.953858 View
ENSG00000010671 BTK ENSG00000149273 RPS3 H. sapiens SDL Slorth 0.953448 View
ENSG00000010671 BTK ENSG00000100906 NFKBIA H. sapiens SDL Slorth 0.953231 View
ENSG00000010671 BTK ENSG00000172531 PPP1CA H. sapiens SDL Slorth 0.953094 View
ENSG00000010671 BTK ENSG00000094804 CDC6 H. sapiens SDL Slorth 0.953012 View
ENSG00000010671 BTK ENSG00000165025 SYK H. sapiens SDL Slorth 0.952909 View
ENSG00000010671 BTK ENSG00000170315 UBB H. sapiens SDL Slorth 0.952355 View
ENSG00000010671 BTK ENSG00000115904 SOS1 H. sapiens SDL Slorth 0.95229 View
ENSG00000010671 BTK ENSG00000141968 VAV1 H. sapiens SDL Slorth 0.952021 View
ENSG00000010671 BTK ENSG00000094916 CBX5 H. sapiens SDL Slorth 0.951932 View
ENSG00000010671 BTK ENSG00000109320 NFKB1 H. sapiens SDL Slorth 0.951751 View
ENSG00000010671 BTK ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.951614 View
ENSG00000010671 BTK ENSG00000144028 SNRNP200 H. sapiens SDL Slorth 0.950958 View
ENSG00000010671 BTK ENSG00000163932 PRKCD H. sapiens SDL Slorth 0.949878 View
ENSG00000010671 BTK ENSG00000100603 SNW1 H. sapiens SDL Slorth 0.949745 View
ENSG00000010671 BTK ENSG00000159352 PSMD4 H. sapiens SDL Slorth 0.949549 View
ENSG00000010671 BTK ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.949484 View
ENSG00000010671 BTK ENSG00000041357 PSMA4 H. sapiens SDL Slorth 0.949443 View
ENSG00000010671 BTK ENSG00000143106 PSMA5 H. sapiens SDL Slorth 0.948918 View
ENSG00000010671 BTK ENSG00000196498 NCOR2 H. sapiens SDL Slorth 0.948817 View
ENSG00000010671 BTK ENSG00000161057 PSMC2 H. sapiens SDL Slorth 0.948736 View
ENSG00000010671 BTK ENSG00000159692 CTBP1 H. sapiens SDL Slorth 0.948651 View
ENSG00000010671 BTK ENSG00000068024 HDAC4 H. sapiens SDL Slorth 0.948549 View
ENSG00000010671 BTK ENSG00000157404 KIT H. sapiens SDL Slorth 0.948524 View
ENSG00000010671 BTK ENSG00000134057 CCNB1 H. sapiens SDL Slorth 0.947773 View
ENSG00000010671 BTK ENSG00000164109 MAD2L1 H. sapiens SDL Slorth 0.947498 View
ENSG00000010671 BTK ENSG00000087191 PSMC5 H. sapiens SDL Slorth 0.946631 View
ENSG00000010671 BTK ENSG00000072062 PRKACA H. sapiens SDL Slorth 0.946354 View
ENSG00000010671 BTK ENSG00000131759 RARA H. sapiens SDL Slorth 0.94491 View
ENSG00000010671 BTK ENSG00000168148 HIST3H3 H. sapiens SDL Slorth 0.944845 View
ENSG00000010671 BTK ENSG00000174775 HRAS H. sapiens SDL Slorth 0.944615 View
ENSG00000010671 BTK ENSG00000108671 PSMD11 H. sapiens SDL Slorth 0.944426 View
ENSG00000010671 BTK ENSG00000126067 PSMB2 H. sapiens SDL Slorth 0.944242 View
ENSG00000010671 BTK ENSG00000154582 TCEB1 H. sapiens SDL Slorth 0.94416 View
ENSG00000010671 BTK ENSG00000147010 SH3KBP1 H. sapiens SDL Slorth 0.943657 View