Go term | Description |
---|---|
GO:0004713 | protein tyrosine kinase activity |
GO:0004714 | transmembrane receptor protein tyrosine kinase activity |
GO:0004872 | receptor activity |
GO:0005088 | Ras guanyl-nucleotide exchange factor activity |
GO:0005509 | calcium ion binding |
GO:0005515 | protein binding |
GO:0005524 | ATP binding |
GO:0005178 | integrin binding |
Drug name | Description |
---|---|
CABOZANTINIB | |
LENVATINIB | |
REGORAFENIB | Tyrosine-protein kinase ABL inhibitor |
SORAFENIB | Serine/threonine-protein kinase RAF inhibitor |
SUNITINIB | Macrophage colony stimulating factor receptor inhibitor |
VANDETANIB | Epidermal growth factor receptor inhibitor |
Disease Name |
---|
medullary thyroid |
papillary thyroid |
pheochromocytoma |
NSCLC |
Spitzoid tumour |
No orthologs in record
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000150991 | UBC | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.990539 | View |
ENSG00000012048 | BRCA1 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.990133 | View |
ENSG00000116478 | HDAC1 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.986581 | View |
ENSG00000091831 | ESR1 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.986563 | View |
ENSG00000005339 | CREBBP | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.985912 | View |
ENSG00000100393 | EP300 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.985567 | View |
ENSG00000100030 | MAPK1 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.984908 | View |
ENSG00000141510 | TP53 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.983987 | View |
ENSG00000132646 | PCNA | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.982778 | View |
ENSG00000142208 | AKT1 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.980726 | View |
ENSG00000080824 | HSP90AA1 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.979963 | View |
ENSG00000165731 | RET | ENSG00000189067 | LITAF | H. sapiens | SDL | Slorth | 0.979516 | View |
ENSG00000165731 | RET | ENSG00000169862 | CTNND2 | H. sapiens | SDL | Slorth | 0.978617 | View |
ENSG00000109670 | FBXW7 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.978235 | View |
ENSG00000133703 | KRAS | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.976421 | View |
ENSG00000165731 | RET | ENSG00000186908 | ZDHHC17 | H. sapiens | SDL | Slorth | 0.975923 | View |
ENSG00000165731 | RET | ENSG00000213949 | ITGA1 | H. sapiens | SDL | Slorth | 0.975023 | View |
ENSG00000135486 | HNRNPA1 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.974088 | View |
ENSG00000165731 | RET | ENSG00000170315 | UBB | H. sapiens | SDL | Slorth | 0.973944 | View |
ENSG00000164305 | CASP3 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.973189 | View |
ENSG00000101266 | CSNK2A1 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.97115 | View |
ENSG00000141736 | ERBB2 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.969987 | View |
ENSG00000132155 | RAF1 | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.969932 | View |
ENSG00000146648 | EGFR | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.969924 | View |
ENSG00000165731 | RET | ENSG00000175376 | EIF1AD | H. sapiens | SDL | Slorth | 0.969674 | View |
ENSG00000142208 | AKT1 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.969429 | View |
ENSG00000165731 | RET | ENSG00000176720 | BOK | H. sapiens | SDL | Slorth | 0.969146 | View |
ENSG00000164924 | YWHAZ | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.968981 | View |
ENSG00000116030 | SUMO1 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.968912 | View |
ENSG00000165731 | RET | ENSG00000185896 | LAMP1 | H. sapiens | SDL | Slorth | 0.968741 | View |
ENSG00000136997 | MYC | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.968084 | View |
ENSG00000105974 | CAV1 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.96802 | View |
ENSG00000128245 | YWHAH | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.967955 | View |
ENSG00000124181 | PLCG1 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.967612 | View |
ENSG00000101146 | RAE1 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.967365 | View |
ENSG00000165731 | RET | ENSG00000182511 | FES | H. sapiens | SDL | Slorth | 0.967295 | View |
ENSG00000082701 | GSK3B | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.966952 | View |
ENSG00000110395 | CBL | ENSG00000165731 | RET | H. sapiens | SDL | Slorth | 0.966599 | View |
ENSG00000165731 | RET | ENSG00000169083 | AR | H. sapiens | SDL | Slorth | 0.966408 | View |
ENSG00000012048 | BRCA1 | ENSG00000165731 | RET | H. sapiens | SSL | Slorth | 0.965999 | View |