RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000130037 KCNA5 ENSG00000165731 RET H. sapiens SSL Slorth 0.753212 View
ENSG00000080603 SRCAP ENSG00000165731 RET H. sapiens SSL Slorth 0.752959 View
ENSG00000162928 PEX13 ENSG00000165731 RET H. sapiens SSL Slorth 0.752559 View
ENSG00000052802 MSMO1 ENSG00000165731 RET H. sapiens SSL Slorth 0.752553 View
ENSG00000111581 NUP107 ENSG00000165731 RET H. sapiens SSL Slorth 0.752471 View
ENSG00000165731 RET ENSG00000169967 MAP3K2 H. sapiens SSL Slorth 0.751986 View
ENSG00000163904 SENP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.750652 View
ENSG00000089737 DDX24 ENSG00000165731 RET H. sapiens SSL Slorth 0.750648 View
ENSG00000131263 RLIM ENSG00000165731 RET H. sapiens SSL Slorth 0.750389 View
ENSG00000068654 POLR1A ENSG00000165731 RET H. sapiens SSL Slorth 0.750145 View