RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000070770 CSNK2A2 ENSG00000165731 RET H. sapiens SSL Slorth 0.761715 View
ENSG00000105364 MRPL4 ENSG00000165731 RET H. sapiens SSL Slorth 0.761685 View
ENSG00000160255 ITGB2 ENSG00000165731 RET H. sapiens SSL Slorth 0.761392 View
ENSG00000078304 PPP2R5C ENSG00000165731 RET H. sapiens SSL Slorth 0.761383 View
ENSG00000148303 RPL7A ENSG00000165731 RET H. sapiens SSL Slorth 0.760891 View
ENSG00000151923 TIAL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.76087 View
ENSG00000163930 BAP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.76059 View
ENSG00000165731 RET ENSG00000215301 DDX3X H. sapiens SSL Slorth 0.760531 View
ENSG00000128340 RAC2 ENSG00000165731 RET H. sapiens SSL Slorth 0.760465 View
ENSG00000136100 VPS36 ENSG00000165731 RET H. sapiens SSL Slorth 0.759667 View
ENSG00000003436 TFPI ENSG00000165731 RET H. sapiens SSL Slorth 0.759532 View
ENSG00000122958 VPS26A ENSG00000165731 RET H. sapiens SSL Slorth 0.759047 View
ENSG00000126858 RHOT1 ENSG00000165731 RET H. sapiens SSL Slorth 0.75892 View
ENSG00000148688 RPP30 ENSG00000165731 RET H. sapiens SSL Slorth 0.758276 View
ENSG00000147955 SIGMAR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.757624 View
ENSG00000129993 CBFA2T3 ENSG00000165731 RET H. sapiens SSL Slorth 0.757538 View
ENSG00000033800 PIAS1 ENSG00000165731 RET H. sapiens SSL Slorth 0.757514 View
ENSG00000067955 CBFB ENSG00000165731 RET H. sapiens SSL Slorth 0.757494 View
ENSG00000165731 RET ENSG00000197694 SPTAN1 H. sapiens SSL Slorth 0.756783 View
ENSG00000152795 HNRNPDL ENSG00000165731 RET H. sapiens SSL Slorth 0.756487 View
ENSG00000139546 TARBP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.756143 View
ENSG00000074211 PPP2R2C ENSG00000165731 RET H. sapiens SSL Slorth 0.7561 View
ENSG00000116062 MSH6 ENSG00000165731 RET H. sapiens SSL Slorth 0.755103 View
ENSG00000133112 TPT1 ENSG00000165731 RET H. sapiens SSL Slorth 0.75509 View
ENSG00000116106 EPHA4 ENSG00000165731 RET H. sapiens SSL Slorth 0.755072 View
ENSG00000164941 INTS8 ENSG00000165731 RET H. sapiens SSL Slorth 0.754715 View
ENSG00000165731 RET ENSG00000187109 NAP1L1 H. sapiens SSL Slorth 0.754623 View
ENSG00000001630 CYP51A1 ENSG00000165731 RET H. sapiens SSL Slorth 0.754591 View
ENSG00000165731 RET ENSG00000173207 CKS1B H. sapiens SSL Slorth 0.754582 View
ENSG00000163939 PBRM1 ENSG00000165731 RET H. sapiens SSL Slorth 0.754555 View
ENSG00000134243 SORT1 ENSG00000165731 RET H. sapiens SSL Slorth 0.754426 View
ENSG00000041357 PSMA4 ENSG00000165731 RET H. sapiens SSL Slorth 0.754161 View
ENSG00000083168 KAT6A ENSG00000165731 RET H. sapiens SSL Slorth 0.754114 View
ENSG00000114686 MRPL3 ENSG00000165731 RET H. sapiens SSL Slorth 0.754015 View
ENSG00000075651 PLD1 ENSG00000165731 RET H. sapiens SSL Slorth 0.753891 View
ENSG00000136930 PSMB7 ENSG00000165731 RET H. sapiens SSL Slorth 0.753755 View
ENSG00000137193 PIM1 ENSG00000165731 RET H. sapiens SSL Slorth 0.75361 View
ENSG00000120837 NFYB ENSG00000165731 RET H. sapiens SSL Slorth 0.753434 View
ENSG00000156603 MED19 ENSG00000165731 RET H. sapiens SSL Slorth 0.753242 View
ENSG00000005175 RPAP3 ENSG00000165731 RET H. sapiens SSL Slorth 0.753231 View