RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000064703 DDX20 ENSG00000165731 RET H. sapiens SSL Slorth 0.827762 View
ENSG00000159210 SNF8 ENSG00000165731 RET H. sapiens SSL Slorth 0.827699 View
ENSG00000111361 EIF2B1 ENSG00000165731 RET H. sapiens SSL Slorth 0.827436 View
ENSG00000121774 KHDRBS1 ENSG00000165731 RET H. sapiens SSL Slorth 0.82742 View
ENSG00000137267 TUBB2A ENSG00000165731 RET H. sapiens SSL Slorth 0.827414 View
ENSG00000139718 SETD1B ENSG00000165731 RET H. sapiens SSL Slorth 0.827084 View
ENSG00000102054 RBBP7 ENSG00000165731 RET H. sapiens SSL Slorth 0.827023 View
ENSG00000126216 TUBGCP3 ENSG00000165731 RET H. sapiens SSL Slorth 0.826961 View
ENSG00000053372 MRTO4 ENSG00000165731 RET H. sapiens SSL Slorth 0.826932 View
ENSG00000109320 NFKB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.826869 View
ENSG00000165731 RET ENSG00000183765 CHEK2 H. sapiens SSL Slorth 0.826764 View
ENSG00000104852 SNRNP70 ENSG00000165731 RET H. sapiens SSL Slorth 0.826384 View
ENSG00000117758 STX12 ENSG00000165731 RET H. sapiens SSL Slorth 0.826233 View
ENSG00000111596 CNOT2 ENSG00000165731 RET H. sapiens SSL Slorth 0.826195 View
ENSG00000042088 TDP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.826186 View
ENSG00000072274 TFRC ENSG00000165731 RET H. sapiens SSL Slorth 0.826022 View
ENSG00000074266 EED ENSG00000165731 RET H. sapiens SSL Slorth 0.825021 View
ENSG00000162409 PRKAA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.825011 View
ENSG00000104142 VPS18 ENSG00000165731 RET H. sapiens SSL Slorth 0.824946 View
ENSG00000152086 TUBA3E ENSG00000165731 RET H. sapiens SSL Slorth 0.824821 View
ENSG00000104517 UBR5 ENSG00000165731 RET H. sapiens SSL Slorth 0.824398 View
ENSG00000165731 RET ENSG00000170734 POLH H. sapiens SSL Slorth 0.824223 View
ENSG00000162736 NCSTN ENSG00000165731 RET H. sapiens SSL Slorth 0.823998 View
ENSG00000005249 PRKAR2B ENSG00000165731 RET H. sapiens SSL Slorth 0.823593 View
ENSG00000153250 RBMS1 ENSG00000165731 RET H. sapiens SSL Slorth 0.823475 View
ENSG00000114503 NCBP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.823356 View
ENSG00000165699 TSC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.823235 View
ENSG00000108262 GIT1 ENSG00000165731 RET H. sapiens SSL Slorth 0.823076 View
ENSG00000099940 SNAP29 ENSG00000165731 RET H. sapiens SSL Slorth 0.822987 View
ENSG00000163629 PTPN13 ENSG00000165731 RET H. sapiens SSL Slorth 0.82267 View
ENSG00000163602 RYBP ENSG00000165731 RET H. sapiens SSL Slorth 0.822564 View
ENSG00000072310 SREBF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.82254 View
ENSG00000106089 STX1A ENSG00000165731 RET H. sapiens SSL Slorth 0.822329 View
ENSG00000149480 MTA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.822265 View
ENSG00000132356 PRKAA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.822004 View
ENSG00000110092 CCND1 ENSG00000165731 RET H. sapiens SSL Slorth 0.821687 View
ENSG00000050748 MAPK9 ENSG00000165731 RET H. sapiens SSL Slorth 0.821606 View
ENSG00000134987 WDR36 ENSG00000165731 RET H. sapiens SSL Slorth 0.821458 View
ENSG00000134250 NOTCH2 ENSG00000165731 RET H. sapiens SSL Slorth 0.821067 View
ENSG00000136717 BIN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.820366 View