RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000121481 RNF2 ENSG00000165731 RET H. sapiens SSL Slorth 0.860963 View
ENSG00000101972 STAG2 ENSG00000165731 RET H. sapiens SSL Slorth 0.860236 View
ENSG00000108055 SMC3 ENSG00000165731 RET H. sapiens SSL Slorth 0.859222 View
ENSG00000160803 UBQLN4 ENSG00000165731 RET H. sapiens SSL Slorth 0.859203 View
ENSG00000092531 SNAP23 ENSG00000165731 RET H. sapiens SSL Slorth 0.859093 View
ENSG00000116141 MARK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.859026 View
ENSG00000065548 ZC3H15 ENSG00000165731 RET H. sapiens SSL Slorth 0.858846 View
ENSG00000100644 HIF1A ENSG00000165731 RET H. sapiens SSL Slorth 0.858755 View
ENSG00000106799 TGFBR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.858587 View
ENSG00000155511 GRIA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.85827 View
ENSG00000155097 ATP6V1C1 ENSG00000165731 RET H. sapiens SSL Slorth 0.858214 View
ENSG00000055130 CUL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.85799 View
ENSG00000149792 MRPL49 ENSG00000165731 RET H. sapiens SSL Slorth 0.857951 View
ENSG00000163681 SLMAP ENSG00000165731 RET H. sapiens SSL Slorth 0.857701 View
ENSG00000130725 UBE2M ENSG00000165731 RET H. sapiens SSL Slorth 0.857355 View
ENSG00000165731 RET ENSG00000168148 HIST3H3 H. sapiens SSL Slorth 0.857267 View
ENSG00000092108 SCFD1 ENSG00000165731 RET H. sapiens SSL Slorth 0.856825 View
ENSG00000150995 ITPR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.856719 View
ENSG00000165731 RET ENSG00000175054 ATR H. sapiens SSL Slorth 0.855961 View
ENSG00000105568 PPP2R1A ENSG00000165731 RET H. sapiens SSL Slorth 0.855916 View
ENSG00000165731 RET ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.855613 View
ENSG00000157020 SEC13 ENSG00000165731 RET H. sapiens SSL Slorth 0.855555 View
ENSG00000164045 CDC25A ENSG00000165731 RET H. sapiens SSL Slorth 0.855523 View
ENSG00000124222 STX16 ENSG00000165731 RET H. sapiens SSL Slorth 0.855269 View
ENSG00000100142 POLR2F ENSG00000165731 RET H. sapiens SSL Slorth 0.855064 View
ENSG00000151461 UPF2 ENSG00000165731 RET H. sapiens SSL Slorth 0.854516 View
ENSG00000131558 EXOC4 ENSG00000165731 RET H. sapiens SSL Slorth 0.854116 View
ENSG00000111859 NEDD9 ENSG00000165731 RET H. sapiens SSL Slorth 0.854009 View
ENSG00000101460 MAP1LC3A ENSG00000165731 RET H. sapiens SSL Slorth 0.853951 View
ENSG00000165731 RET ENSG00000170004 CHD3 H. sapiens SSL Slorth 0.853641 View
ENSG00000143801 PSEN2 ENSG00000165731 RET H. sapiens SSL Slorth 0.853618 View
ENSG00000134014 ELP3 ENSG00000165731 RET H. sapiens SSL Slorth 0.853576 View
ENSG00000072062 PRKACA ENSG00000165731 RET H. sapiens SSL Slorth 0.853351 View
ENSG00000126458 RRAS ENSG00000165731 RET H. sapiens SSL Slorth 0.853256 View
ENSG00000147416 ATP6V1B2 ENSG00000165731 RET H. sapiens SSL Slorth 0.853252 View
ENSG00000165731 RET ENSG00000166913 YWHAB H. sapiens SSL Slorth 0.852561 View
ENSG00000138107 ACTR1A ENSG00000165731 RET H. sapiens SSL Slorth 0.852518 View
ENSG00000165731 RET ENSG00000166226 CCT2 H. sapiens SSL Slorth 0.852273 View
ENSG00000001167 NFYA ENSG00000165731 RET H. sapiens SSL Slorth 0.851928 View
ENSG00000087586 AURKA ENSG00000165731 RET H. sapiens SSL Slorth 0.851455 View