RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000137834 SMAD6 ENSG00000165731 RET H. sapiens SSL Slorth 0.890594 View
ENSG00000110713 NUP98 ENSG00000165731 RET H. sapiens SSL Slorth 0.890371 View
ENSG00000119335 SET ENSG00000165731 RET H. sapiens SSL Slorth 0.889987 View
ENSG00000136450 SRSF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.889891 View
ENSG00000096063 SRPK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.889307 View
ENSG00000106070 GRB10 ENSG00000165731 RET H. sapiens SSL Slorth 0.888722 View
ENSG00000077063 CTTNBP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.888565 View
ENSG00000105011 ASF1B ENSG00000165731 RET H. sapiens SSL Slorth 0.888498 View
ENSG00000106211 HSPB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.888329 View
ENSG00000165731 RET ENSG00000173039 RELA H. sapiens SSL Slorth 0.88825 View
ENSG00000033327 GAB2 ENSG00000165731 RET H. sapiens SSL Slorth 0.888239 View
ENSG00000119772 DNMT3A ENSG00000165731 RET H. sapiens SSL Slorth 0.888124 View
ENSG00000136997 MYC ENSG00000165731 RET H. sapiens SSL Slorth 0.888008 View
ENSG00000141867 BRD4 ENSG00000165731 RET H. sapiens SSL Slorth 0.887943 View
ENSG00000140807 NKD1 ENSG00000165731 RET H. sapiens SSL Slorth 0.887879 View
ENSG00000165731 RET ENSG00000169045 HNRNPH1 H. sapiens SSL Slorth 0.887711 View
ENSG00000007168 PAFAH1B1 ENSG00000165731 RET H. sapiens SSL Slorth 0.887677 View
ENSG00000165731 RET ENSG00000169375 SIN3A H. sapiens SSL Slorth 0.887273 View
ENSG00000120738 EGR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.887164 View
ENSG00000065675 PRKCQ ENSG00000165731 RET H. sapiens SSL Slorth 0.886958 View
ENSG00000139197 PEX5 ENSG00000165731 RET H. sapiens SSL Slorth 0.886777 View
ENSG00000112335 SNX3 ENSG00000165731 RET H. sapiens SSL Slorth 0.886545 View
ENSG00000105976 MET ENSG00000165731 RET H. sapiens SSL Slorth 0.886182 View
ENSG00000049759 NEDD4L ENSG00000165731 RET H. sapiens SSL Slorth 0.886121 View
ENSG00000162231 NXF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.886022 View
ENSG00000129691 ASH2L ENSG00000165731 RET H. sapiens SSL Slorth 0.885667 View
ENSG00000094880 CDC23 ENSG00000165731 RET H. sapiens SSL Slorth 0.885541 View
ENSG00000101412 E2F1 ENSG00000165731 RET H. sapiens SSL Slorth 0.88505 View
ENSG00000147044 CASK ENSG00000165731 RET H. sapiens SSL Slorth 0.884996 View
ENSG00000103769 RAB11A ENSG00000165731 RET H. sapiens SSL Slorth 0.884485 View
ENSG00000103197 TSC2 ENSG00000165731 RET H. sapiens SSL Slorth 0.884224 View
ENSG00000133895 MEN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.884146 View
ENSG00000165731 RET ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.884118 View
ENSG00000165731 RET ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.884025 View
ENSG00000133794 ARNTL ENSG00000165731 RET H. sapiens SSL Slorth 0.883268 View
ENSG00000072110 ACTN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.882741 View
ENSG00000100083 GGA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.882707 View
ENSG00000164109 MAD2L1 ENSG00000165731 RET H. sapiens SSL Slorth 0.882124 View
ENSG00000130726 TRIM28 ENSG00000165731 RET H. sapiens SSL Slorth 0.881717 View
ENSG00000036257 CUL3 ENSG00000165731 RET H. sapiens SSL Slorth 0.88147 View