DNMT3A

ENSG00000119772 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0005515 protein binding
GO:0009008 DNA-methyltransferase activity
GO:0042802 identical protein binding
GO:0045322 unmethylated CpG binding
GO:0046872 metal ion binding
GO:0051718 DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

Drugs

Drug name Description
AZACITIDINE DNA (cytosine-5)-methyltransferase 1 inhibitor
DECITABINE DNA (cytosine-5)-methyltransferase 1 inhibitor

Diseases

Disease Name
AML

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000116478 HDAC1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.98803 View
ENSG00000005339 CREBBP ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.981606 View
ENSG00000100393 EP300 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.981219 View
ENSG00000103275 UBE2I ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.980927 View
ENSG00000012048 BRCA1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.980219 View
ENSG00000119772 DNMT3A ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.978719 View
ENSG00000119772 DNMT3A ENSG00000150991 UBC H. sapiens SDL Slorth 0.977621 View
ENSG00000113558 SKP1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.976796 View
ENSG00000091831 ESR1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.976718 View
ENSG00000119772 DNMT3A ENSG00000133703 KRAS H. sapiens SSL Slorth 0.974891 View
ENSG00000101266 CSNK2A1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.974311 View
ENSG00000109670 FBXW7 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.974257 View
ENSG00000119772 DNMT3A ENSG00000170315 UBB H. sapiens SDL Slorth 0.97399 View
ENSG00000119772 DNMT3A ENSG00000132646 PCNA H. sapiens SDL Slorth 0.97263 View
ENSG00000119772 DNMT3A ENSG00000141510 TP53 H. sapiens SDL Slorth 0.971878 View
ENSG00000119772 DNMT3A ENSG00000169083 AR H. sapiens SDL Slorth 0.970321 View
ENSG00000082701 GSK3B ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.968765 View
ENSG00000100030 MAPK1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.968165 View
ENSG00000119772 DNMT3A ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.967152 View
ENSG00000112592 TBP ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.965624 View
ENSG00000100644 HIF1A ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.964182 View
ENSG00000116030 SUMO1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.962966 View
ENSG00000119772 DNMT3A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.962853 View
ENSG00000119772 DNMT3A ENSG00000173039 RELA H. sapiens SDL Slorth 0.962051 View
ENSG00000101266 CSNK2A1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.961469 View
ENSG00000119772 DNMT3A ENSG00000139687 RB1 H. sapiens SDL Slorth 0.959115 View
ENSG00000055130 CUL1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.958899 View
ENSG00000012048 BRCA1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.958337 View
ENSG00000005339 CREBBP ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.957583 View
ENSG00000002016 RAD52 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.957003 View
ENSG00000119772 DNMT3A ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.955107 View
ENSG00000119772 DNMT3A ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.955065 View
ENSG00000102882 MAPK3 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.954804 View
ENSG00000110092 CCND1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.953925 View
ENSG00000119772 DNMT3A ENSG00000185591 SP1 H. sapiens SDL Slorth 0.952954 View
ENSG00000119772 DNMT3A ENSG00000171720 HDAC3 H. sapiens SDL Slorth 0.952771 View
ENSG00000110395 CBL ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.952426 View
ENSG00000082701 GSK3B ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.952243 View
ENSG00000107643 MAPK8 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.949214 View
ENSG00000113575 PPP2CA ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.949203 View