DNMT3A

ENSG00000119772 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0005515 protein binding
GO:0009008 DNA-methyltransferase activity
GO:0042802 identical protein binding
GO:0045322 unmethylated CpG binding
GO:0046872 metal ion binding
GO:0051718 DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

Drugs

Drug name Description
AZACITIDINE DNA (cytosine-5)-methyltransferase 1 inhibitor
DECITABINE DNA (cytosine-5)-methyltransferase 1 inhibitor

Diseases

Disease Name
AML

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000080824 HSP90AA1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.949192 View
ENSG00000119772 DNMT3A ENSG00000136997 MYC H. sapiens SDL Slorth 0.949127 View
ENSG00000119772 DNMT3A ENSG00000170312 CDK1 H. sapiens SDL Slorth 0.948387 View
ENSG00000103275 UBE2I ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.948148 View
ENSG00000119772 DNMT3A ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.947759 View
ENSG00000097046 CDC7 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.947722 View
ENSG00000100030 MAPK1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.947665 View
ENSG00000109320 NFKB1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.94661 View
ENSG00000119772 DNMT3A ENSG00000169375 SIN3A H. sapiens SDL Slorth 0.946057 View
ENSG00000072401 UBE2D1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.94588 View
ENSG00000068024 HDAC4 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.945839 View
ENSG00000113575 PPP2CA ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.944627 View
ENSG00000109906 ZBTB16 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.943765 View
ENSG00000112062 MAPK14 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.942737 View
ENSG00000119772 DNMT3A ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.942432 View
ENSG00000112592 TBP ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.94226 View
ENSG00000119772 DNMT3A ENSG00000177606 JUN H. sapiens SDL Slorth 0.941261 View
ENSG00000119772 DNMT3A ENSG00000196498 NCOR2 H. sapiens SDL Slorth 0.941125 View
ENSG00000051180 RAD51 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.940897 View
ENSG00000094916 CBX5 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.940731 View
ENSG00000113558 SKP1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.939988 View
ENSG00000097007 ABL1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.939518 View
ENSG00000106462 EZH2 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.939357 View
ENSG00000091831 ESR1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.939086 View
ENSG00000096717 SIRT1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.938656 View
ENSG00000101146 RAE1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.938476 View
ENSG00000064393 HIPK2 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.938191 View
ENSG00000101412 E2F1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.937887 View
ENSG00000004700 RECQL ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.936762 View
ENSG00000119772 DNMT3A ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.935864 View
ENSG00000119772 DNMT3A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.935101 View
ENSG00000104365 IKBKB ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.933211 View
ENSG00000119772 DNMT3A ENSG00000140464 PML H. sapiens SDL Slorth 0.933185 View
ENSG00000119772 DNMT3A ENSG00000145386 CCNA2 H. sapiens SSL Slorth 0.932449 View
ENSG00000119772 DNMT3A ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.931718 View
ENSG00000101665 SMAD7 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.930416 View
ENSG00000119772 DNMT3A ENSG00000136450 SRSF1 H. sapiens SSL Slorth 0.929595 View
ENSG00000119772 DNMT3A ENSG00000150459 SAP18 H. sapiens SSL Slorth 0.92832 View
ENSG00000101412 E2F1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.928169 View
ENSG00000102054 RBBP7 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.927555 View