DNMT3A - MYC

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
DNMT3A ENSG00000119772 AML
AZACITIDINE
DECITABINE
DNA binding
chromatin binding
DNA (cytosine-5-)-methyltransferase activity
protein binding
DNA-methyltransferase activity
identical protein binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

No GO terms in record

MYC ENSG00000136997 Burkitt lymphoma
amplified in other cancers
B-CLL

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein complex binding
protein dimerization activity
repressing transcription factor binding
E-box binding

No GO terms in record