DNMT3A

ENSG00000119772 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0005515 protein binding
GO:0009008 DNA-methyltransferase activity
GO:0042802 identical protein binding
GO:0045322 unmethylated CpG binding
GO:0046872 metal ion binding
GO:0051718 DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

Drugs

Drug name Description
AZACITIDINE DNA (cytosine-5)-methyltransferase 1 inhibitor
DECITABINE DNA (cytosine-5)-methyltransferase 1 inhibitor

Diseases

Disease Name
AML

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000119772 DNMT3A ENSG00000124486 USP9X H. sapiens SSL Slorth 0.88464 View
ENSG00000119772 DNMT3A ENSG00000283094 PTEN H. sapiens SSL Slorth 0.883586 View
ENSG00000119772 DNMT3A ENSG00000170345 FOS H. sapiens SSL Slorth 0.883525 View
ENSG00000119772 DNMT3A ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.883374 View
ENSG00000119772 DNMT3A ENSG00000139842 CUL4A H. sapiens SSL Slorth 0.881313 View
ENSG00000119772 DNMT3A ENSG00000141564 RPTOR H. sapiens SSL Slorth 0.880888 View
ENSG00000049759 NEDD4L ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.880639 View
ENSG00000119772 DNMT3A ENSG00000132341 RAN H. sapiens SSL Slorth 0.880188 View
ENSG00000082898 XPO1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.877369 View
ENSG00000096968 JAK2 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.877101 View
ENSG00000119772 DNMT3A ENSG00000175054 ATR H. sapiens SSL Slorth 0.876097 View
ENSG00000119772 DNMT3A ENSG00000197299 BLM H. sapiens SSL Slorth 0.875014 View
ENSG00000119772 DNMT3A ENSG00000187555 USP7 H. sapiens SSL Slorth 0.874997 View
ENSG00000010810 FYN ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.874463 View
ENSG00000119772 DNMT3A ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.874254 View
ENSG00000117399 CDC20 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.874135 View
ENSG00000119772 DNMT3A ENSG00000166501 PRKCB H. sapiens SSL Slorth 0.873921 View
ENSG00000119772 DNMT3A ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.873777 View
ENSG00000119772 DNMT3A ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.873094 View
ENSG00000070010 UFD1L ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.872113 View
ENSG00000108443 RPS6KB1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.872003 View
ENSG00000119772 DNMT3A ENSG00000147010 SH3KBP1 H. sapiens SSL Slorth 0.871826 View
ENSG00000119772 DNMT3A ENSG00000138376 BARD1 H. sapiens SSL Slorth 0.871027 View
ENSG00000062822 POLD1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.869485 View
ENSG00000119772 DNMT3A ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.869125 View
ENSG00000119772 DNMT3A ENSG00000185787 MORF4L1 H. sapiens SSL Slorth 0.867509 View
ENSG00000119772 DNMT3A ENSG00000134308 YWHAQ H. sapiens SSL Slorth 0.867219 View
ENSG00000119772 DNMT3A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.866331 View
ENSG00000119772 DNMT3A ENSG00000162231 NXF1 H. sapiens SSL Slorth 0.866135 View
ENSG00000114767 RRP9 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.864057 View
ENSG00000004897 CDC27 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.863806 View
ENSG00000112118 MCM3 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.862791 View
ENSG00000119772 DNMT3A ENSG00000135486 HNRNPA1 H. sapiens SSL Slorth 0.862735 View
ENSG00000119772 DNMT3A ENSG00000124813 RUNX2 H. sapiens SSL Slorth 0.861695 View
ENSG00000119772 DNMT3A ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.86152 View
ENSG00000119772 DNMT3A ENSG00000153147 SMARCA5 H. sapiens SSL Slorth 0.860261 View
ENSG00000119772 DNMT3A ENSG00000151247 EIF4E H. sapiens SSL Slorth 0.860244 View
ENSG00000119772 DNMT3A ENSG00000168283 BMI1 H. sapiens SSL Slorth 0.858746 View
ENSG00000119772 DNMT3A ENSG00000169398 PTK2 H. sapiens SSL Slorth 0.85837 View
ENSG00000119772 DNMT3A ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.858273 View