DNMT3A

ENSG00000119772 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0005515 protein binding
GO:0009008 DNA-methyltransferase activity
GO:0042802 identical protein binding
GO:0045322 unmethylated CpG binding
GO:0046872 metal ion binding
GO:0051718 DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

Drugs

Drug name Description
AZACITIDINE DNA (cytosine-5)-methyltransferase 1 inhibitor
DECITABINE DNA (cytosine-5)-methyltransferase 1 inhibitor

Diseases

Disease Name
AML

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000119772 DNMT3A ENSG00000136518 ACTL6A H. sapiens SSL Slorth 0.81966 View
ENSG00000093009 CDC45 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.81914 View
ENSG00000084774 CAD ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.816661 View
ENSG00000104738 MCM4 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.816032 View
ENSG00000119772 DNMT3A ENSG00000137693 YAP1 H. sapiens SSL Slorth 0.815723 View
ENSG00000119772 DNMT3A ENSG00000149136 SSRP1 H. sapiens SSL Slorth 0.815222 View
ENSG00000119772 DNMT3A ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.814465 View
ENSG00000107581 EIF3A ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.814228 View
ENSG00000105568 PPP2R1A ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.811519 View
ENSG00000119772 DNMT3A ENSG00000164109 MAD2L1 H. sapiens SSL Slorth 0.810847 View
ENSG00000116288 PARK7 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.808969 View
ENSG00000085840 ORC1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.806819 View
ENSG00000119772 DNMT3A ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.806639 View
ENSG00000087586 AURKA ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.805041 View
ENSG00000110330 BIRC2 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.802854 View
ENSG00000079999 KEAP1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.802405 View
ENSG00000102978 POLR2C ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.801548 View
ENSG00000101161 PRPF6 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.801282 View
ENSG00000119772 DNMT3A ENSG00000183431 SF3A3 H. sapiens SSL Slorth 0.801206 View
ENSG00000119772 DNMT3A ENSG00000137486 ARRB1 H. sapiens SSL Slorth 0.800956 View
ENSG00000119772 DNMT3A ENSG00000141543 EIF4A3 H. sapiens SSL Slorth 0.7996 View
ENSG00000119772 DNMT3A ENSG00000148606 POLR3A H. sapiens SSL Slorth 0.798122 View
ENSG00000115816 CEBPZ ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.797929 View
ENSG00000006451 RALA ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.796038 View
ENSG00000119772 DNMT3A ENSG00000139343 SNRPF H. sapiens SSL Slorth 0.795733 View
ENSG00000119772 DNMT3A ENSG00000127511 SIN3B H. sapiens SSL Slorth 0.795716 View
ENSG00000036257 CUL3 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.792931 View
ENSG00000099817 POLR2E ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.791144 View
ENSG00000070950 RAD18 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.788619 View
ENSG00000070756 PABPC1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.788065 View
ENSG00000119772 DNMT3A ENSG00000130332 LSM7 H. sapiens SSL Slorth 0.787026 View
ENSG00000101665 SMAD7 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.786119 View
ENSG00000103126 AXIN1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.784933 View
ENSG00000080503 SMARCA2 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.781969 View
ENSG00000119772 DNMT3A ENSG00000254772 EEF1G H. sapiens SSL Slorth 0.780626 View
ENSG00000119772 DNMT3A ENSG00000129559 NEDD8 H. sapiens SSL Slorth 0.780231 View
ENSG00000119772 DNMT3A ENSG00000127022 CANX H. sapiens SSL Slorth 0.779895 View
ENSG00000119772 DNMT3A ENSG00000164362 TERT H. sapiens SSL Slorth 0.777994 View
ENSG00000080815 PSEN1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.777607 View
ENSG00000119772 DNMT3A ENSG00000172936 MYD88 H. sapiens SSL Slorth 0.776743 View