DNMT3A

ENSG00000119772 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0005515 protein binding
GO:0009008 DNA-methyltransferase activity
GO:0042802 identical protein binding
GO:0045322 unmethylated CpG binding
GO:0046872 metal ion binding
GO:0051718 DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

Drugs

Drug name Description
AZACITIDINE DNA (cytosine-5)-methyltransferase 1 inhibitor
DECITABINE DNA (cytosine-5)-methyltransferase 1 inhibitor

Diseases

Disease Name
AML

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000119772 DNMT3A ENSG00000134086 VHL H. sapiens SSL Slorth 0.927135 View
ENSG00000119772 DNMT3A ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.924585 View
ENSG00000119772 DNMT3A ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.923773 View
ENSG00000119772 DNMT3A ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.923768 View
ENSG00000109971 HSPA8 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.923753 View
ENSG00000119772 DNMT3A ENSG00000166851 PLK1 H. sapiens SSL Slorth 0.923645 View
ENSG00000111276 CDKN1B ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.923165 View
ENSG00000119772 DNMT3A ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.923014 View
ENSG00000110092 CCND1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.922943 View
ENSG00000114166 KAT2B ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.92276 View
ENSG00000111642 CHD4 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.921772 View
ENSG00000119772 DNMT3A ENSG00000165392 WRN H. sapiens SSL Slorth 0.920609 View
ENSG00000096384 HSP90AB1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.920436 View
ENSG00000119772 DNMT3A ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.919852 View
ENSG00000119772 DNMT3A ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.917677 View
ENSG00000113721 PDGFRB ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.917301 View
ENSG00000105229 PIAS4 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.916339 View
ENSG00000077097 TOP2B ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.915568 View
ENSG00000119772 DNMT3A ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.915416 View
ENSG00000100644 HIF1A ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.915166 View
ENSG00000080503 SMARCA2 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.914423 View
ENSG00000119772 DNMT3A ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.914421 View
ENSG00000100906 NFKBIA ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.913783 View
ENSG00000119772 DNMT3A ENSG00000124762 CDKN1A H. sapiens SDL Slorth 0.91357 View
ENSG00000096384 HSP90AB1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.912887 View
ENSG00000100811 YY1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.912852 View
ENSG00000119772 DNMT3A ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.912153 View
ENSG00000119772 DNMT3A ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.911043 View
ENSG00000119772 DNMT3A ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.910775 View
ENSG00000119772 DNMT3A ENSG00000175792 RUVBL1 H. sapiens SDL Slorth 0.910108 View
ENSG00000119772 DNMT3A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.909849 View
ENSG00000119772 DNMT3A ENSG00000169045 HNRNPH1 H. sapiens SSL Slorth 0.909351 View
ENSG00000101945 SUV39H1 ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.909063 View
ENSG00000119772 DNMT3A ENSG00000156970 BUB1B H. sapiens SSL Slorth 0.908716 View
ENSG00000119772 DNMT3A ENSG00000129152 MYOD1 H. sapiens SSL Slorth 0.908335 View
ENSG00000119772 DNMT3A ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.907896 View
ENSG00000101868 POLA1 ENSG00000119772 DNMT3A H. sapiens SSL Slorth 0.907846 View
ENSG00000119772 DNMT3A ENSG00000134982 APC H. sapiens SSL Slorth 0.906522 View
ENSG00000119772 DNMT3A ENSG00000135018 UBQLN1 H. sapiens SSL Slorth 0.906069 View
ENSG00000119772 DNMT3A ENSG00000132170 PPARG H. sapiens SSL Slorth 0.905697 View